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Stem cell factor/c-kit system in spermatogenesis.
One of the major unresolved questions with male infertility is the identification of the molecular origin of a great majority of the spermatogenetic arrests currently diagnosed as idiopathic maleExpand
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Leukemia Inhibitory Factor Is a Key Signal for Injury-Induced Neurogenesis in the Adult Mouse Olfactory Epithelium
The mammalian olfactory epithelium (OE) is composed of primary olfactory sensory neurons (OSNs) that are renewed throughout adulthood by local, restricted neuronal progenitor cells. The molecularExpand
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Long-term apoptotic cell death process with increased expression and activation of caspase-3 and -6 in adult rat germ cells exposed in utero to flutamide.
Although it is established that in utero exposure to antiandrogenic compounds such as flutamide induces hypospermatogenesis in adult male rat offspring, the cellular and molecular mechanisms remainExpand
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The mitochondrial-dependent pathway is chronically affected in testicular germ cell death in adult rats exposed in utero to anti-androgens.
In utero exposure to exogenous anti-androgenic compounds induces a wide range of abnormalities of the reproductive system, including hypospermatogenesis, cryptorchidism and hypospadias. By using ratsExpand
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Cellular distribution of EGF, TGFα and their receptor during postnatal development and spermatogenesis of the boar testis
The epidermal growth factor (EGF), the transforming growth factor alpha (TGFalpha) and the epidermal growth factor receptor (EGFr) have been immunolocalized, (i) during the testicular postnatalExpand
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The inhibitory effects on adult male reproductive functions of crude garlic (Allium sativum) feeding.
AIM to investigate the effects of crude garlic on adult male rat reproductive functions. METHODS Thirty male rats were divided into five groups: group 1 (untreated) and groups 2, 3, 4 and 5 wereExpand
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Developmental and hormonal regulation of the expression of oligodendrocyte-specific protein/claudin 11 in mouse testis.
The proliferation and differentiation of testicular progenitor stem cells into highly specialized germ cells (spermatozoa) are largely controlled by the hormonally (FSH and testosterone) regulatedExpand
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Regulation by pH of the Alternative Splicing of the Stem Cell Factor Pre-mRNA in the Testis*
Proliferation and differentiation of progenitor stem cells are mainly controlled by diffusible and adhesion molecules. Stem cell factor (SCF), an essential regulator of spermatogenesis produced byExpand
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Tumor necrosis factor-alpha -308 polymorphism in infertile men with altered sperm production or motility.
BACKGROUND One of the most well-documented cytokines suspected as a hazard to male fertility is tumor necrosis factor-alpha (TNFalpha). Genetic factors such as single-nucleotide polymorphisms (SNPs)Expand
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Alteration of transforming growth factor-beta signaling system expression in adult rat germ cells with a chronic apoptotic cell death process after fetal androgen disruption.
In utero exposure to chemicals with antiandrogen activity induces undescended testis, hypospadias, and sub- or infertility. The hypospermatogenesis observed in the adult rat testis exposed in uteroExpand
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