AFN 1252

Known as: AFN-1252, AFN1252 
 
National Institutes of Health

Topic mentions per year

Topic mentions per year

2009-2016
012320092016

Papers overview

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2015
2015
AIMS AFN-1252 is a novel inhibitor of FabI, an essential enzyme in Staphylococcus spp. This study was undertaken to assess the… (More)
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2015
2015
This open-label noncontrolled, phase II multicenter trial was designed to evaluate the safety, tolerability, and efficacy of 200… (More)
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2013
2013
This study examines the alteration in Staphylococcus aureus gene expression following treatment with the type 2 fatty acid… (More)
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2013
2013
OBJECTIVES To investigate the absorption, distribution, metabolism and excretion of AFN-1252, a novel inhibitor of the essential… (More)
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2013
2013
AFN-1252 is a potent antibiotic against Staphylococcus aureus that targets the enoyl-acyl carrier protein reductase (FabI). A… (More)
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2013
2013
AFN-1252, a new antimicrobial agent, specifically and potently inhibits fatty acid synthesis in Staphylococcus aureus. We… (More)
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2013
2013
AFN-1252 is a novel inhibitor of FabI, an essential enzyme in fatty acid biosynthesis in Staphylococcus spp. AFN-1252 exhibits… (More)
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2013
2013
AFN-1252, a potent enoyl-ACP reductase (FabI) inhibitor, is under development for the treatment of Staphylococcus aureus… (More)
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2012
2012
The mechanism of action of AFN-1252, a selective inhibitor of Staphylococcus aureus enoyl-acyl carrier protein reductase (FabI… (More)
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2009
2009
AFN-1252, a potent inhibitor of enoyl-acyl carrier protein reductase (FabI), inhibited all clinical isolates of Staphylococcus… (More)
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