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AF-9 protein

Known as: Myeloid/Lymphoid or Mixed-Lineage Leukemia Translocated to Chromosome 3 Protein, Trithorax Homolog 3, YEATS Domain-Containing Protein 3 
Protein AF-9 (568 aa, ~63 kDa) is encoded by the human MLLT3 gene. This protein may play a role in the regulation of transcription.
National Institutes of Health

Related topics

Related topics

7 relations
DNA-Binding ProteinsGenes, RegulatorMLLT3 geneMLLT3 wt Allele

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Different neuropeptides are expressed in different functional subsets of cholinergic excitatory motorneurons in the nematode Ascaris suum.
Neuropeptides are known to have dramatic effects on neurons and synapses; however, despite extensive studies of the motorneurons… 
Review
2015
Review
2015
Regulation of αENaC transcription.
Review
2014
Review
2014
MYELOID NEOPLASIA shRNA screening identi fi es JMJD 1 C as being required for leukemia maintenance
Translocations involvingmixed lineage leukemia (MLL) gene occur frequently in acute leukemia, especially in childhood and… 
2013
2013
An Af9 cis-element directly targets Dot1a to mediate transcriptional repression of the αENaC gene.
The epithelial Na(+) channel subunit-α (αENaC) of the distal nephron is essential for salt balance. We previously demonstrated… 
2013
2013
Sp1 trans-activates and is required for maximal aldosterone induction of the αENaC gene in collecting duct cells.
The epithelial Na+ channel (ENaC) in the distal nephron constitutes the rate-limiting step for renal sodium reabsorption… 
2012
2012
Spironolactone Rescues Dot1a-Af9-Mediated Repression of Endothelin-1 and Improves Kidney Injury in Streptozotocin-Induced Diabetic Rats
The molecular mechanism linking aldosterone and endothelin-1 in the development of diabetic nephropathy has not been completely… 
2012
2012
Etoposide-induced apoptosis results in chromosome breaks within the AF9 gene: Its implication in chromosome rearrangement in leukaemia
Treatment with etoposide (VP-16) has been associated with translocation of the mixed lineage leukaemia (MLL) gene seen in… 
2009
2009
The planar cell polarity (PCP) protein Diversin translocates to the nucleus to interact with the transcription factor AF9.
Review
2009
Review
2009
The Robotic Mouse: Understanding the Role of AF4, a Cofactor of Transcriptional Elongation and Chromatin Remodelling, in Purkinje Cell Function
Neurological disorders represent a large share of the disease burden worldwide, and the incidence of age-related forms will… 
Highly Cited
1980
Highly Cited
1980
Divalent antibodies to mouse embryonal carcinoma cells inhibit compaction in the mouse embryo.
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