ADP-ribosyl Cyclase

Known as: ADP-ribosyl Cyclase [Chemical/Ingredient], Adenosine Diphosphate Ribose Cyclase, ADP ribosyl cyclase 
A membrane-bound or cytosolic enzyme that catalyzes the synthesis of CYCLIC ADP-RIBOSE (cADPR) from nicotinamide adenine dinucleotide (NAD). This… (More)
National Institutes of Health

Papers overview

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2009
2009
AIMS Here, we report the discovery of a small molecule inhibitor, 2,2'-dihydroxyazobenzene (DAB), of ADP ribosyl cyclase (ADPR… (More)
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2009
2009
ADP ribosyl (ADPR) cyclases comprise a family of ectoenzymes recently shown to influence cytosolic Ca(2+) concentration in a… (More)
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2008
2008
ADP-ribosyl cyclase (ADPR cyclase) and ryanodine receptors (RyR) participate in calcium transduction in isolated afferent… (More)
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2007
2007
An important role for the enzyme ADP-ribosyl cyclase (ADPR cyclase) and its downstream targets, the ryanodine receptors (RyR), is… (More)
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Review
2005
Review
2005
Poly(ADP-ribosyl) ation is a reversible post-translational protein modification implicated in the regulation of a number of… (More)
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2003
2003
Cyclic ADP-ribose, a metabolite of NAD+, is known to modulate intracellular calcium levels and signaling in various cell types… (More)
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1999
1999
The multifunctional ADP-ribosyl cyclase, CD38, catalyzes the cyclization of NAD(+) to cyclic ADP-ribose (cADPr). The latter gates… (More)
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1999
1999
The multifunctional ADP-ribosyl cyclase, CD38, catalyzes the cyclization of NAD 1 to cyclic ADP-ribose (cADPr). The latter gates… (More)
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Highly Cited
1998
Highly Cited
1998
Poly(ADP-ribose) polymerase (PARP) (EC 2.4.2.30), the only enzyme known to synthesize ADP-ribose polymers from NAD+, is activated… (More)
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Highly Cited
1995
Highly Cited
1995
Poly(ADP-ribosyl)ation is catalyzed by NAD+: protein(ADP-ribosyl) transferase (ADPRT), a chromatin-associated enzyme which, in… (More)
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