ADME Study

Known as: ADME, Absorption, Distribution, Metabolism and Excretion, Absorption, Distribution, Metabolism, and Excretion Study 
A group of pharmacokinetic parameters commonly investigated during preclinical drug development.
National Institutes of Health

Papers overview

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Review
2014
Review
2014
  • Li Di
  • The AAPS Journal
  • 2014
Development of peptide drugs is challenging but also quite rewarding. Five blockbuster peptide drugs are currently on the market… (More)
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Review
2012
Review
2012
The concept of treating cancer with antibody-drug conjugates (ADCs) has gained momentum with the favorable activity and safety of… (More)
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Highly Cited
2008
Highly Cited
2008
New updated! The latest book from a very famous author finally comes out. Book of drug like properties concepts structure design… (More)
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Highly Cited
2008
Highly Cited
2008
DrugBank is a richly annotated resource that combines detailed drug data with comprehensive drug target and drug action… (More)
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Highly Cited
2008
Highly Cited
2008
Drug discovery and chemical biology are exceedingly complex and demanding enterprises. In recent years there are been increasing… (More)
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Highly Cited
2007
Highly Cited
2007
A critically evaluated database of human intestinal absorption for 648 chemical compounds is reported in this study, among which… (More)
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Review
2006
Review
2006
There have recently been developments in the methods used to access the accuracy of the prediction and applicability domain of… (More)
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2002
2002
Absorption, distribution, metabolism and excretion (ADME) studies, are widely used in drug discovery to optimize the balance of… (More)
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Review
2000
Review
2000
There are currently about 10000 drug-like compounds. These are sparsely, rather than uniformly, distributed through chemistry… (More)
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Highly Cited
2000
Highly Cited
2000
Rational drug discovery requires an early appraisal of all factors impacting on the likely success of a drug candidate in the… (More)
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