ADAM17 Protein

Known as: ADAM17 Protein [Chemical/Ingredient], TNF-alpha Convertase, ADAM-17 
A disintegrin and metalloproteinase domain-containing protein that cleaves the membrane-bound precursor of TUMOR NECROSIS FACTOR-ALPHA to its mature… (More)
National Institutes of Health

Topic mentions per year

Topic mentions per year

1998-2018
0102019982018

Papers overview

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2010
2010
Pref-1/Dlk1 is made as an epidermal growth factor (EGF) repeat-containing transmembrane protein but is cleaved by tumor necrosis… (More)
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2007
Highly Cited
2007
Endothelial protein C receptor (EPCR) plays an important role in the protein C anticoagulation pathway. Previously, we have… (More)
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2006
Highly Cited
2006
Ectodomain shedding has emerged as an important regulatory step in the function of transmembrane proteins. Intercellular adhesion… (More)
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2005
Highly Cited
2005
Cytokine and extracellular matrix (ECM) homeostasis are distinct systems that are each dysregulated in heart failure. Here we… (More)
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2004
2004
Cannabinoids, the active components of marijuana and their endogenous counterparts were reported as useful analgetic agents to… (More)
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2003
Highly Cited
2003
Tumor necrosis factor-alpha converting enzyme (TACE) is a prototype member of the adamalysin family of transmembrane… (More)
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2003
Highly Cited
2003
MUC1 clearance from the uterine epithelial cell surface is a prerequisite for the creation of an environment conducive to embryo… (More)
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2001
Highly Cited
2001
The beta-amyloid precursor protein (APP) is a ubiquitous receptor-like molecule without a known function. However, the recent… (More)
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2000
Highly Cited
2000
Membrane type 4 matrix metalloproteinase (MT4-MMP) shows the least sequence homology to the other MT-MMPs, suggesting a distinct… (More)
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Highly Cited
1998
Highly Cited
1998
TNF-alpha converting enzyme (TACE; ADAM-17) is a membrane-bound disintegrin metalloproteinase that processes the membrane… (More)
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