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ABT-578

Known as: ABT 578, ABT578 
National Institutes of Health

Related topics

Related topics

1 relation

Broader (1)

zotarolimus

Papers overview

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Review
2006
Review
2006
[Interventional cardiology in 2005].
Drug-eluting stents have been shown to reduce the rate of restenosis significantly in all types of lesion, patient and clinical… 
2005
2005
Stent‐based delivery of ABT‐578 via a phosphorylcholine surface coating reduces neointimal formation in the porcine coronary model
Stent‐based delivery of the antiproliferative and immunosuppressive macrocyclic lactone sirolimus reduces neointimal formation… 
2005
2005
Pharmacokinetics and Safety of ABT-578, a Sirolimus (Rapamycin) Analogue, after Single Intravenous Bolus Injection in Healthy Male Volunteers
AbstractObjective: ABT-578, a tetrazole analogue of sirolimus (rapamycin), possesses anti-restenosis activity. The aim of this… 
2005
2005
A Phase I Multiple‐Dose Escalation Study Characterizing Pharmacokinetics and Safety of ABT‐578 in Healthy Subjects
ABT‐578, a sirolimus analog, is being developed for administration from drug‐eluting stents to prevent postimplantation… 
2005
2005
Complete assignments of the 1H and 13C resonances of 40‐epi‐(N1‐tetrazolyl)‐rapamycin and revised 13C assignments for rapamycin
  • T. Pagano
  • Magnetic resonance in chemistry : MRC
  • 2005
  • Corpus ID: 34024654
Complete 1H and 13C assignments of 40‐epi‐(N1‐tetrazolyl)‐rapamycin (ABT‐578) in DMSO‐d6 were made using 1H, 13C, DQCOSY, ROESY… 
Review
2004
Review
2004
ABT-578-Eluting Stents
Abstract.ABT-578 is a new synthetic analog of rapamycin, designed to inhibit smooth muscle cell proliferation—a key contributor… 
2004
2004
Method development for the quantitation of ABT-578 in rabbit artery tissue by 96-well liquid-liquid extraction and liquid chromatography/tandem mass spectrometric detection.
Quantitative determination of drug concentrations in tissue samples can provide critical information for drug metabolism… 
2004
2004
96-Well liquid-liquid extraction liquid chromatography-tandem mass spectrometry method for the quantitative determination of ABT-578 in human blood samples.
Review
2004
Review
2004
[When are drug-eluting stents effective? A critical analysis of the presently available data].
The use of drugeluting stents (DES) has tackled the "Achilles' heel" of percutaneous coronary interventions (PCI) like no… 
2002
2002
Quantification of plasma and intracellular levels of the HIV protease inhibitor ritonavir by competitive ELISA.
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