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This study sought to report the final 5-year outcomes of the ENDEAVOR IV (A Randomized, Controlled Trial of the… Expand Drug-eluting stents have revolutionized the field of interventional cardiology and have provided a significant innovation for… Expand Drug-eluting stents (DESs) have shown significant promise at reducing rates of restenosis and subsequent revascularization… Expand Stent‐based delivery of the antiproliferative and immunosuppressive macrocyclic lactone sirolimus reduces neointimal formation… Expand We report here a specific, automated LC/LC-MS/MS assay for the quantification of ABT-578 in human and rabbit blood and rabbit… Expand AbstractObjective: ABT-578, a tetrazole analogue of sirolimus (rapamycin), possesses anti-restenosis activity. The aim of this… Expand The introduction of drug-eluting stents (DES) to interventional cardiology practice has resulted in a significant improvement in… Expand Abstract.ABT-578 is a new synthetic analog of rapamycin, designed
to inhibit smooth muscle cell proliferation—a key contributor… Expand We report here a quantitative method for the analysis of ABT-578 in human whole blood samples. Sample preparation was achieved by… Expand Quantitative determination of drug concentrations in tissue samples can provide critical information for drug metabolism… Expand