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ABT 431

Known as: ABT-431, DAS-431 
 
National Institutes of Health

Papers overview

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Highly Cited
2006
Highly Cited
2006
RationaleD1-Like agonists are self-administered by drug-naive animals, whereas D2-like agonists reinstate cocaine-seeking… Expand
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Highly Cited
2004
Highly Cited
2004
A natural consequence of aging is a loss of dopamine function and associated deficits in working memory in both human and… Expand
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Highly Cited
2001
Highly Cited
2001
BACKGROUND Dyskinesias are a frequent adverse effect of long-term levodopa therapy. The relative contribution of dopamine D(1… Expand
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Review
2001
Review
2001
Adrogolide (ABT-431; DAS-431) is a chemically stable prodrug that is converted rapidly (<1 min) in plasma to A-86929, a full… Expand
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2001
2001
Methods: We studied ABT-431, the prodrug of a fully selective D1 agonist, in 20 subjects with advanced Parkinson disease and a… Expand
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2000
2000
Selective D1 dopamine agonists represent a potential pharmacotherapy for the treatment of cocaine addiction. Here we report that… Expand
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Highly Cited
1999
Highly Cited
1999
Rationale: Data in laboratory animals suggest that D1 receptor agonists may have potential utility for the treatment of cocaine… Expand
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1999
1999
Studies in animal models show a selective D1 receptor agonist with full functional efficacy compared with dopamine to have… Expand
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1996
1996
(-)-Trans 9,10-hydroxy-2-propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5- azacyclopent-1-ena[c]phenanthrene hydrochloride (A-86929) is a… Expand
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1996
1996
A-86929 ((-)-trans-9,10-dihydroxy-2-propyl-4,5,5a,6,7,11b-hexahydro-3- thia-5-azacyclopent-1-ena[c]phenanthrene) is a potent and… Expand
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