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ABCC1 protein, human

Known as: ATP-Binding Cassette Sub-Family C Member 1, Multidrug Resistance-Associated Protein 1, ATP-binding cassette, sub-family C (CFTR-MRP), member 1, human 
Multidrug resistance-associated protein 1 (1531 aa, ~172 kDa) is encoded by the human ABCC1 gene. This protein plays a role in the cellular export of… 
National Institutes of Health

Related topics

Related topics

19 relations
ABCC1 geneAdenosine TriphosphatasesCellular MembraneDrug Efflux

Broader (1)

Multidrug Resistance Associated Protein 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2011
2011
Monomethylarsenic Diglutathione Transport by the Human Multidrug Resistance Protein 1 (MRP1/ABCC1)
The ATP-binding cassette (ABC) transporter protein multidrug resistance protein 1 (MRP1; ABCC1) plays an important role in the… 
2010
2010
Expression and Function of Human MRP1 (ABCC1) Is Dependent on Amino Acids in Cytoplasmic Loop 5 and Its Interface with Nucleotide Binding Domain 2*
Multidrug resistance protein 1 (MRP1) is an ATP-binding cassette transporter that effluxes drugs and organic anions across the… 
2009
2009
ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts
Objective The ATP-binding cassette transporter ABCC1 [i.e. multidrug resistance-associated protein 1 (MRP1)] is a membrane-bound… 
2005
2005
Role of two adjacent cytoplasmic tyrosine residues in MRP1 (ABCC1) transport activity and sensitivity to sulfonylureas.
2005
2005
Analysis of Human Multidrug Resistance Protein 1 (ABCC1) by Matrix-Assisted Laser Desorption Ionization/Time of Flight Mass Spectrometry: Toward Identification of Leukotriene C4 Binding Sites
Multidrug resistance in tumor cells may be caused by reduced drug accumulation resulting from expression of one or more proteins… 
2005
2005
Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites.
2002
2002
Low level of mitochondrial deoxyguanosine kinase is the dominant factor in acquired resistance to 9-beta-D-arabinofuranosylguanine cytotoxicity.
2002
2002
Impact of BCRP/MXR, MRP1 and MDR1/P‐Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells
The impact of the ABC transporters breast cancer resistance protein/mitoxantrone resistance associated transporter (BCRP/MXR… 
2002
2002
Dehydrothyrsiferol does not modulate multidrug resistance-associated protein 1 resistance: a functional screening system for MRP1 substrates.
We had shown previously that the novel, marine, anticancer compound dehydrothyrsiferol (DHT) does not modulate P-glycoprotein (P… 
Highly Cited
2001
Highly Cited
2001
Identification of an Amino Acid Residue in Multidrug Resistance Protein 1 Critical for Conferring Resistance to Anthracyclines*
Murine multidrug resistance protein 1 (mrp1), unlike human MRP1, does not confer resistance to anthracyclines. Previously, we… 
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