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ABCC1 protein, human

Known as: ATP-Binding Cassette Sub-Family C Member 1, Multidrug Resistance-Associated Protein 1, ATP-binding cassette, sub-family C (CFTR-MRP), member 1, human 
Multidrug resistance-associated protein 1 (1531 aa, ~172 kDa) is encoded by the human ABCC1 gene. This protein plays a role in the cellular export of… Expand
National Institutes of Health

Papers overview

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Review
2018
Review
2018
Intercellular communications play a major role in tissue homeostasis. In pathologies such as cancer, cellular interactions within… Expand
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Highly Cited
2011
Highly Cited
2011
In Alzheimer disease (AD), the intracerebral accumulation of amyloid-β (Aβ) peptides is a critical yet poorly understood process… Expand
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Highly Cited
2010
Highly Cited
2010
Cancer cells that develop resistance to chemotherapeutic agents are a major clinical obstacle in the successful treatment of… Expand
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Highly Cited
2009
Highly Cited
2009
C(4) photosynthesis is an adaptive trait conferring an advantage in warm and open habitats. It originated multiple times and is… Expand
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Highly Cited
2009
Highly Cited
2009
Imatinib mesylate and nilotinib are highly effective at eradicating the majority of chronic myeloid leukemia (CML) cells; however… Expand
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Highly Cited
2006
Highly Cited
2006
Nitrogen monoxide (NO) plays a role in the cytotoxic mechanisms of activated macrophages against tumor cells by inducing iron (Fe… Expand
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Highly Cited
2005
Highly Cited
2005
Flavonoids are a class of polyphenolic compounds widely present in the diet and herbal products. The interactions of flavonoids… Expand
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Highly Cited
2004
Highly Cited
2004
Unconjugated bilirubin (UCB) causes encephalopathy in severely jaundiced neonates by damaging astrocytes and neurons. Astrocytes… Expand
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Highly Cited
2000
Highly Cited
2000
The multidrug resistance-associated protein 1 (MRP1) and the canalicular multispecific organic anion transporter (cMOAT or MRP2… Expand
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Highly Cited
1999
Highly Cited
1999
Intrinsic and/or acquired resistance to chemotherapy is the major obstacle to overcome in the treatment of patients with ovarian… Expand
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