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ABCC1 protein, human

Known as: ATP-Binding Cassette Sub-Family C Member 1, Multidrug Resistance-Associated Protein 1, ATP-binding cassette, sub-family C (CFTR-MRP), member 1, human 
Multidrug resistance-associated protein 1 (1531 aa, ~172 kDa) is encoded by the human ABCC1 gene. This protein plays a role in the cellular export of… 
National Institutes of Health

Papers overview

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Review
2014
Review
2014
  • Y. Choi, A. Yu
  • Current pharmaceutical design
  • 2014
  • Corpus ID: 25068525
Multidrug resistance (MDR) is a serious problem that hampers the success of cancer pharmacotherapy. A common mechanism is the… 
Highly Cited
2011
Highly Cited
2011
In Alzheimer disease (AD), the intracerebral accumulation of amyloid-β (Aβ) peptides is a critical yet poorly understood process… 
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Highly Cited
2010
Highly Cited
2010
Cancer cells that develop resistance to chemotherapeutic agents are a major clinical obstacle in the successful treatment of… 
Highly Cited
2009
Highly Cited
2009
Imatinib mesylate and nilotinib are highly effective at eradicating the majority of chronic myeloid leukemia (CML) cells; however… 
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Review
2006
Review
2006
MRP1 (ABCC1) is a peculiar member of the ABC transporter superfamily for several aspects. This protein has an unusually broad… 
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Highly Cited
2006
Highly Cited
2006
Nitrogen monoxide (NO) plays a role in the cytotoxic mechanisms of activated macrophages against tumor cells by inducing iron (Fe… 
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Highly Cited
2005
Highly Cited
2005
Flavonoids are a class of polyphenolic compounds widely present in the diet and herbal products. The interactions of flavonoids… 
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Highly Cited
2004
Highly Cited
2004
Unconjugated bilirubin (UCB) causes encephalopathy in severely jaundiced neonates by damaging astrocytes and neurons. Astrocytes… 
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Highly Cited
2000
Highly Cited
2000
The multidrug resistance-associated protein 1 (MRP1) and the canalicular multispecific organic anion transporter (cMOAT or MRP2… 
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Highly Cited
1999
Highly Cited
1999
Intrinsic and/or acquired resistance to chemotherapy is the major obstacle to overcome in the treatment of patients with ovarian… 
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