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ABCC1 protein, human

Known as: ATP-Binding Cassette Sub-Family C Member 1, Multidrug Resistance-Associated Protein 1, ATP-binding cassette, sub-family C (CFTR-MRP), member 1, human 
Multidrug resistance-associated protein 1 (1531 aa, ~172 kDa) is encoded by the human ABCC1 gene. This protein plays a role in the cellular export of… 
National Institutes of Health

Related topics

Related topics

19 relations
ABCC1 geneAdenosine TriphosphatasesCellular MembraneDrug Efflux

Broader (1)

Multidrug Resistance Associated Protein 1

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2015
2015
Oxidation of the GaAs semiconductor at the Al2O3/GaAs junction.
Atomic-scale understanding and processing of the oxidation of III-V compound-semiconductor surfaces are essential for developing… 
2014
2014
Modulation of ABCC1 and ABCG2 proteins by ouabain in human breast cancer cells.
ABCC1 and ABCG2 are two transporters associated with multi-drug resistance to cancer chemotherapy. Ouabain is a cardiotonic… 
2011
2011
The Antiepileptic Drugs Phenobarbital and Carbamazepine Reduce Transport of Methotrexate in Rat Choroid Plexus by Down-Regulation of the Reduced Folate Carrier
Intrathecal methotrexate (MTX) has been associated with severe neurotoxicity. Because carrier-associated removal of MTX from the… 
2010
2010
Expression and Function of Human MRP1 (ABCC1) Is Dependent on Amino Acids in Cytoplasmic Loop 5 and Its Interface with Nucleotide Binding Domain 2*
Multidrug resistance protein 1 (MRP1) is an ATP-binding cassette transporter that effluxes drugs and organic anions across the… 
2009
2009
ABCC1 polymorphisms contribute to level and decline of lung function in two population-based cohorts
Objective The ATP-binding cassette transporter ABCC1 [i.e. multidrug resistance-associated protein 1 (MRP1)] is a membrane-bound… 
2005
2005
Analysis of Human Multidrug Resistance Protein 1 (ABCC1) by Matrix-Assisted Laser Desorption Ionization/Time of Flight Mass Spectrometry: Toward Identification of Leukotriene C4 Binding Sites
Multidrug resistance in tumor cells may be caused by reduced drug accumulation resulting from expression of one or more proteins… 
2005
2005
Limited modulation of the transport activity of the human multidrug resistance proteins MRP1, MRP2 and MRP3 by nicotine glucuronide metabolites.
2003
2003
Expressions of hepatobiliary organic anion transporters and bilirubin-conjugating enzyme in differentiating embryonic stem cells.
2002
2002
Impact of BCRP/MXR, MRP1 and MDR1/P‐Glycoprotein on thermoresistant variants of atypical and classical multidrug resistant cancer cells
The impact of the ABC transporters breast cancer resistance protein/mitoxantrone resistance associated transporter (BCRP/MXR… 
2002
2002
Dehydrothyrsiferol does not modulate multidrug resistance-associated protein 1 resistance: a functional screening system for MRP1 substrates.
We had shown previously that the novel, marine, anticancer compound dehydrothyrsiferol (DHT) does not modulate P-glycoprotein (P… 
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