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A3309

 
National Institutes of Health

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1 relation

Broader (1)

elobixibat

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Erratum: A randomized placebo-controlled phase IIb trial of A3309, a bile acid transporter inhibitor, for chronic idiopathic constipation (American Journal of Gastroenterology (2011) 34 (41-50))
 
2012
2012
Altered Bile Acid Pool Using IBAT Inhibitors for Constipation: A Potentially Increased Risk of Malignancy
Altered Bile Acid Pool Using IBAT Inhibitors for Constipation: A Potentially Increased Risk of Malignancy 
2012
2012
Vaccinations While On Thiopurines: Some Protection Is Better Than None
  • G. Melmed
  • The American Journal of Gastroenterology
  • 2012
    • Corpus ID: 9164015
ileal resection for causes other than Crohn ’ s disease) have not been associated with an increased incidence of CRC. In the… Expand
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2012
2012
Response to Drs Trivedi and Ward
To the Editor: We read with great interest the article by Chey et al. (1), which demonstrated promising results in the treatment… Expand
Highly Cited
2011
Highly Cited
2011
A Randomized Placebo-Controlled Phase IIb Trial of A3309, A Bile Acid Transporter Inhibitor, for Chronic Idiopathic Constipation
OBJECTIVES:A3309 is a minimally absorbed ileal bile acid (BA) transporter (IBAT) inhibitor. We conducted an 8-week, multicenter… Expand
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Highly Cited
2011
Highly Cited
2011
Randomised clinical trial: the ileal bile acid transporter inhibitor A3309 vs. placebo in patients with chronic idiopathic constipation – a double‐blind study
Aliment Pharmacol Ther 2011; 34: 41–50 
Highly Cited
2011
Highly Cited
2011
Effects of A3309, an Ileal Bile Acid Transporter Inhibitor, on Colonic Transit and Symptoms in Females With Functional Constipation
OBJECTIVES:Delivery of bile acid (BA) to the colon stimulates propulsive motility and fluid secretion. The objective of this… Expand
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2011
2011
Effects of A3309, an Ileal Bile Acid Transporter Inhibitor, on Colonic Transit and Symptoms in Patients with Functional Constipation
3OBJECTIVES: Delivery of bile acid (BA) to the colon stimulates propulsive motility and fl uid secretion. The objective of this… Expand
2011
2011
A3309, an Ileal Bile Acid Transport (IBAT /ASBT) Inhibitor, Significantly Improved Stool Frequency and Other Constipation-Related Complaints in Adults With Chronic Constipation: Data From an 8-Week…
and symptoms while subjects were at their highest dose (last 7 days of treatment period) versus placebo, adjusting for… Expand
2010
2010
S1302 Dose-Related Effects of Chenodeoxycholate on Gastrointestinal and Colonic Transit and Bowel Function in Female Patients With Constipation-Predominant Irritable Bowel Syndrome
Background: A3309 modulates the enterohepatic circulation of bile acids (BA) by inhibiting the intestinal bile acid transporter… Expand
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