• Publications
  • Influence
Functional Bowel Disorders.
TLDR
Advances in the understanding of the pathophysiology of FBD, particularly IBS, published in Gastroenterology has led to the current appreciation that FBD represent dysfunction in the bidirectional brain-gut axis, intestinal barrier dysfunction and interactions with the microbiota and dietary factors. Expand
The Central Role of Gastrointestinal-Specific Anxiety in Irritable Bowel Syndrome: Further Validation of the Visceral Sensitivity Index
TLDR
The VSI demonstrated excellent psychometric properties providing further support for its use in mechanistic studies of the role of anxiety in irritable bowel syndrome presentation. Expand
Sensation of bloating and visible abdominal distension in patients with irritable bowel syndrome
TLDR
Bloating and visible abdominal distension may arise from two distinct but interrelated physiological processes and may be related to triggering of a visceromotor reflex affecting the tone of abdominal wall muscles. Expand
Gender, age, society, culture, and the patient's perspective in the functional gastrointestinal disorders.
TLDR
There is evidence for sex- and gender-related differences in FGID, particularly irritable bowel syndrome (IBS), and there appears to be a greater clinical response to serotonergic agents developed for IBS in women compared to men. Expand
Longitudinal change in perceptual and brain activation response to visceral stimuli in irritable bowel syndrome patients.
TLDR
In IBS patients, repeated exposure to experimental aversive visceral stimuli results in the habituation of visceral perception and central arousal, despite stable activation of networks processing visceral pain and its anticipation. Expand
Differences in somatic perception in female patients with irritable bowel syndrome with and without fibromyalgia
TLDR
Both hypervigilance and somatic hypoalgesia contribute to the altered somatic perception in IBS patients, and co‐morbidity with FM results in somatic hyperalgesa in Ibs patients. Expand
Gender differences in irritable bowel syndrome.
TLDR
Although gender differences in the therapeutic benefit of serotonergic agents have been observed, less is known about potential differences in responsiveness to nondrug therapies for irritable bowel syndrome. Expand
Gender-related differences in IBS symptoms
TLDR
Female patients report higher levels of a variety of intestinal and nonintestinal sensory symptoms despite similar levels of IBS severity, abdominal pain, psychological symptoms, and illness impact, making it unlikely that most of the gender differences observed are directly tied to the menstrual cycle. Expand
A Focus Group Assessment of Patient Perspectives on Irritable Bowel Syndrome and Illness Severity
TLDR
Focus groups conducted to address the growing need to understand from the patient’s perspective the experience of irritable bowel syndrome and the factors contributing to its severity confirmed the heterogeneous and multi-component nature of IBS. Expand
Irritable Bowel Syndrome Patients Show Enhanced Modulation of Visceral Perception by Auditory Stress
TLDR
Findings confirm the hypothesis that altered stress-induced modulation of visceral perception in IBS patients shows altered perceptual responses to rectal balloon distention during experimentally induced psychological stress. Expand
...
1
2
3
4
5
...