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A 86929

Known as: A-86929 
 
National Institutes of Health

Papers overview

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2011
2011
A-86929, a dopamine D1 agonist was synthesized with 95% ee in five steps with overall yield of 56% via catalytic enantioselective… Expand
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Review
2009
Review
2009
The dopamine (DA) D1 receptor is the most highly expressed DA receptor subtype among the DA receptor family. Although the first… Expand
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2004
2004
The straightforward methodology for the construction of chiral arene-fused-piperidine motifs using a highly enantioselective… Expand
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Review
2001
Review
2001
Adrogolide (ABT-431; DAS-431) is a chemically stable prodrug that is converted rapidly (<1 min) in plasma to A-86929, a full… Expand
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1999
1999
Abstract Common marmosets show parkinsonian motor deficits following 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP… Expand
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Highly Cited
1999
Highly Cited
1999
Studies in animal models show a selective D1 receptor agonist with full functional efficacy compared with dopamine to have… Expand
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1997
1997
The clinical utility of dopamine (DA) D1 receptor agonists in the treatment of Parkinson's disease (PD) is still unclear. The… Expand
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1997
1997
The ability of the selective dopamine D1 receptor agonist (5aR,11bS)-4,5,5a,6,7,11b-hexahydro-2-propyl-3-thia-5-aza cyclopent-1… Expand
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Highly Cited
1996
Highly Cited
1996
(-)-Trans 9,10-hydroxy-2-propyl-4,5,5a,6,7,11b-hexahydro-3-thia-5- azacyclopent-1-ena[c]phenanthrene hydrochloride (A-86929) is a… Expand
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1996
1996
A-86929 ((-)-trans-9,10-dihydroxy-2-propyl-4,5,5a,6,7,11b-hexahydro-3- thia-5-azacyclopent-1-ena[c]phenanthrene) is a potent and… Expand
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