Skip to search form
Skip to main content
Skip to account menu
Semantic Scholar
Semantic Scholar's Logo
Search 225,190,168 papers from all fields of science
Search
Sign In
Create Free Account
A 64662
Known as:
A-64662
, Abbott 64662
, Abbott-64662
National Institutes of Health
Create Alert
Alert
Related topics
Related topics
1 relation
Broader (1)
enalkiren
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
1992
1992
C-terminal modifications of nonpeptide renin inhibitors: improved oral bioavailability via modification of physicochemical properties.
S. Boyd
,
A. Fung
,
+7 authors
V. Klinghofer
Journal of Medicinal Chemistry
1992
Corpus ID: 32560209
We describe the development of a series of soluble, potent, and bioavailable nonpeptide renin inhibitors. These inhibitors…
Expand
1990
1990
Prolonged Duration of Blood Pressure Response to Enalkiren, the Novel Dipeptide Renin Inhibitor, in Essential Hypertension
R. Boger
,
H. Glassman
,
+6 authors
R. Luther
HYPERTENSION
1990
Corpus ID: 487458
The effects of sustained renin inhibition by repeated administration of enalkiren (A- 64662), the novel dipeptide renin inhibitor…
Expand
1990
1990
Effects of a Novel Renin Inhibitor in Patients with Essential Hypertension
M. Bursztyn
,
I. Gavras
,
C. Tifft
,
R. Luther
,
R. Boger
,
H. Gavras
Journal of Cardiovascular Pharmacology
1990
Corpus ID: 24224287
The effects of A-64662, a new specific renin inhibitor, on plasma renin activity (PRA) and blood pressure (BP) were studied for…
Expand
Review
1990
Review
1990
Clinical pharmacology of enalkiren, a novel, dipeptide renin inhibitor.
H. Glassman
,
H. Kleinert
,
R. Boger
,
D. Moyse
,
A. Griffiths
,
R. Luther
Journal of Cardiovascular Pharmacology
1990
Corpus ID: 31383514
Enalkiren (A-64662), a potent, dipeptide renin inhibitor, mimics the transition state of the human renin substrate…
Expand
1989
1989
Effects of chronic infusion of renin inhibitor A-64662 in sodium-depleted monkeys.
K. Verburg
,
H. Kleinert
,
J. Kadam
,
M. Chekal
,
P. Mento
,
B. Wílkes
HYPERTENSION
1989
Corpus ID: 6642639
The potent and primate-selective renin inhibitor A-64662 (n = 8) or vehicle (n = 6) was administered intravenously for 7 days to…
Expand
Highly Cited
1989
Highly Cited
1989
Hemodynamic and Humoral Effects of the New Renin Inhibitor Enalkiren in Normal Humans
A. Delabays
,
Jiirg Nussberger
,
+7 authors
H. Brunner
HYPERTENSION
1989
Corpus ID: 22845782
The effect of the renin inhibitor enalkiren (Abbott- 64662) was evaluated in eight normal volunteer subjects on a standardized…
Expand
1989
1989
Renin inhibition with A-64662: effect on blood pressure and hormonal response in man.
M. Bursztyn
,
I. Gavras
,
C. Tifft
,
J. Bauer
,
J. Melby
,
H. Gavras
Journal of Hypertension - Supplement
1989
Corpus ID: 41999340
We studied the effects of intravenous injections of the renin inhibitor A-64662 on blood pressure, plasma renin activity (PRA…
Expand
1988
1988
Effects of the Renin Inhibitor A‐64662 in Monkeys and Rats with Varying Baseline Plasma Renin Activity
H. Kleinert
,
D. Martin
,
+5 authors
R. Luther
HYPERTENSION
1988
Corpus ID: 12528032
The efficacy of the potent, primate selective renin inhibitor A-64662 was studied in monkeys and rats with varying baseline…
Expand
By clicking accept or continuing to use the site, you agree to the terms outlined in our
Privacy Policy
(opens in a new tab)
,
Terms of Service
(opens in a new tab)
, and
Dataset License
(opens in a new tab)
ACCEPT & CONTINUE