Skip to search formSkip to main contentSkip to account menu
You are currently offline. Some features of the site may not work correctly.

enalkiren

Known as: (Alpha-S)-Alpha-((Alpha-S)-Alpha-(3-Amino-3-Methylbutyramido)-p-Methoxyhydrocinnamamido)-N-((1S,2R,3S)-1-(Cyclohexylmethyl)-2,3-Dihydroxy-5-Methylhexyl)Imidazole-4-Propionamide, (N-(3-amino-3-methyl-1-oxobutyl)-4-methoxy-L-phenylalanyl)-N-(1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl)-L-histidinamide, L-Histidinamide, N-(3-amino-3-methyl-1-oxobutyl)-O-methyl-L-tyrosyl-N-(1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl)-, (1S-(1R*,2S*,3R*))- 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2005
2005
SummaryPolypeptides, synthesized from a mixture of amino acid amides by microwave heating during repeated hydration-dehydration… Expand
  • figure 1
  • table 2
  • table 1
  • figure 2
  • figure 3
1995
1995
Renin inhibition represents an alternative to angiotensin‐converting enzyme (ACE) inhibition for pharmacologic interruption of… Expand
Highly Cited
1994
Highly Cited
1994
We compared the renal vascular responses to angiotensin converting enzyme inhibition and renin inhibition to assess the influence… Expand
  • table 1
  • table 2
  • figure 2
  • figure 3
  • table 3
1992
1992
We describe the development of a series of soluble, potent, and bioavailable nonpeptide renin inhibitors. These inhibitors… Expand
1991
1991
Interpretation of renin-angiotensin blockade with angiotensin converting enzyme inhibitors is potentially confounded by their… Expand
  • table 1
  • figure 1
  • figure 2
  • figure 4
1991
1991
Previous efforts to block the renin-angiotensin system in patients with chronic congestive heart failure (CHF) have focused on 2… Expand
1991
1991
The antihypertensive effects of the renin inhibitor enalkiren were compared with those of the angiotensin-converting enzyme… Expand
1990
1990
The effects of sustained renin inhibition by repeated administration of enalkiren (A- 64662), the novel dipeptide renin inhibitor… Expand
Review
1990
Review
1990
Enalkiren (A-64662), a potent, dipeptide renin inhibitor, mimics the transition state of the human renin substrate… Expand
1989
1989
The effect of the renin inhibitor enalkiren (Abbott- 64662) was evaluated in eight normal volunteer subjects on a standardized… Expand
  • figure 1
  • figure 2
  • figure 3
  • figure 4
  • figure 5