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enalkiren

Known as: (Alpha-S)-Alpha-((Alpha-S)-Alpha-(3-Amino-3-Methylbutyramido)-p-Methoxyhydrocinnamamido)-N-((1S,2R,3S)-1-(Cyclohexylmethyl)-2,3-Dihydroxy-5-Methylhexyl)Imidazole-4-Propionamide, (N-(3-amino-3-methyl-1-oxobutyl)-4-methoxy-L-phenylalanyl)-N-(1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl)-L-histidinamide, L-Histidinamide, N-(3-amino-3-methyl-1-oxobutyl)-O-methyl-L-tyrosyl-N-(1-(cyclohexylmethyl)-2,3-dihydroxy-5-methylhexyl)-, (1S-(1R*,2S*,3R*))- 
 
National Institutes of Health

Papers overview

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2005
2005
SummaryPolypeptides, synthesized from a mixture of amino acid amides by microwave heating during repeated hydration-dehydration… Expand
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Highly Cited
1994
Highly Cited
1994
We compared the renal vascular responses to angiotensin converting enzyme inhibition and renin inhibition to assess the influence… Expand
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1992
1992
We describe the development of a series of soluble, potent, and bioavailable nonpeptide renin inhibitors. These inhibitors… Expand
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1991
1991
Previous efforts to block the renin-angiotensin system in patients with chronic congestive heart failure (CHF) have focused on 2… Expand
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1991
1991
Interpretation of renin-angiotensin blockade with angiotensin converting enzyme inhibitors is potentially confounded by their… Expand
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1991
1991
The antihypertensive effects of the renin inhibitor enalkiren were compared with those of the angiotensin-converting enzyme… Expand
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1990
1990
The effects of sustained renin inhibition by repeated administration of enalkiren (A- 64662), the novel dipeptide renin inhibitor… Expand
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Review
1990
Review
1990
Enalkiren (A-64662), a potent, dipeptide renin inhibitor, mimics the transition state of the human renin substrate… Expand
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1990
1990
Corneal application of enalkiren (ABBOTT-64662), [N-(3-amino-3-methyl-1- oxobutyl)-4-methoxy-L-phenylalanyl]-N-[1S,2R,3S)-1… Expand
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1989
1989
The effect of the renin inhibitor enalkiren (Abbott- 64662) was evaluated in eight normal volunteer subjects on a standardized… Expand
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