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A 147627
Known as:
A-147627
National Institutes of Health
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Related topics
1 relation
atrasentan
Papers overview
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2008
2008
Endothelin-3-dependent pulmonary vasoconstriction in monocrotaline-induced pulmonary arterial hypertension
S. Sauvageau
,
É. Thorin
,
L. Villeneuve
,
J. Dupuis
Peptides
2008
Corpus ID: 3424246
2005
2005
High-throughput determination of atrasentan in human plasma by high-performance liquid chromatography coupled with electrospray ionization tandem mass spectrometry.
Perry G Wang
,
Jack Wei
,
Min-Su Chang
,
T. El-Shourbagy
Biomedical chromotography
2005
Corpus ID: 24355428
Atrasentan (A-147627) is an endothelin antagonist receptor being developed at Abbott Laboratories for the treatment of prostate…
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1998
1998
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 3. Discovery of a potent, 2-nonaryl, highly selective ETA antagonist (A-216546).
G. Liu
,
K. Henry
,
+11 authors
T. Opgenorth
Journal of Medicinal Chemistry
1998
Corpus ID: 24234102
Previously we have reported the discovery of ABT-627 (1, A-147627, active enantiomer of A-127722), a 2,4-diaryl substituted…
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1997
1997
Pyrrolidine-3-carboxylic acids as endothelin antagonists. 2. Sulfonamide-based ETA/ETB mixed antagonists.
H. Jae
,
M. Winn
,
+4 authors
T. V. von Geldern
Journal of Medicinal Chemistry
1997
Corpus ID: 21995668
When the N,N-dialkylacetamide side chain of the highly ETA-selective endothelin antagonist ABT-627 (1; [2R,3R,4S]-2-(4…
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