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A 033

Known as: A-033, A033, AO-33 
National Institutes of Health

Related topics

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1 relation

Broader (1)

losigame

Papers overview

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2018
2018
Abstract A033: Concordance of IHC and a new blood-based expression assay for the detection of PD-L1 in patients diagnosed with NSCLC
Introduction: Therapeutic options for patients with non-small cell lung cancer (NSCLC) continue to expand with the approval of… 
2016
2016
Abstract A033: Phase Ia study of FoxP3+ CD4 Treg depletion by infusion of a humanized anti-CCR4 antibody, KW-0761, in cancer patients
Purpose: FoxP3+ Tregs inhibit immune responses against tumors. KW-0761 is a humanized anti-human CCR4 monoclonal antibody (mAb… 
2010
2010
Pharmacokinetics of [14C]-labelled losigamone and enantiomers after oral administration to healthy subjects
SummaryLosigamone ((±)-(R*, S*)-5-(2-chlorophenylhydroxymethyl)-4-methoxy-2 (5H)-furanone; AO-33) is a new potential… 
2004
2004
Comparison of the effects of losigamone and its isomers on maximal electroshock induced convulsions in mice and on three different patterns of low magnesium induced epileptiform activity in slices of…
SummaryLosigamone (AO-33) is a recemate of a tetronic acid derivative. The effects of losigamone and its three isomers (AO-242… 
2004
2004
Influence of Losigamone on the Pharmacokinetics of a Combined Oral Contraceptive in Healthy Female Volunteers
Summary Objectives: The influence of the new anti-epileptic drug losigamone (CAS 112856-44-7 / 123783-52-8) on the… 
2000
2000
A033: Impact of antihypertensive treatment on left ventricular geometric patterns: The preserve study
1999
1999
A033: Different techniques of blood pressure measurements and their relation with target organ involvements of hypertension
1998
1998
A033: The effects of angiotensin II (AII), endothelin-1 (ET1) and protein kinase C (PKC) inhibitor on DNA synthesis and cytosolic calcium (Ca++) mobilization in VSMC's of WKY and SHR
1997
1997
The effect of losigamone (AO‐33) on electrical activity and excitatory amino acid release in mouse cortical slices
1 Losigamone is a novel anticonvulsant the mechanism of action of which is not known. This study investigated the effect of… 
1996
1996
Pharmacokinetics of losigamone, a new antiepileptic drug, in healthy male volunteers.
Losigamone (AO-33), a new potential antiepileptic drug, was tested in 52 healthy male volunteers in 4 placebo-controlled phase I… 
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