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9-deazainosine

National Institutes of Health

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2 relations

Broader (1)

Inosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2002
2002
Atomic dissection of the hydrogen bond network for transition-state analogue binding to purine nucleoside phosphorylase.
Immucillin-H (ImmH) and immucillin-G (ImmG) were previously reported as transition-state analogues for bovine purine nucleoside… 
2001
2001
Stereocontrolled syntheses of carbocyclic C-nucleosides and related compounds.
Carbocyclic 9-deazapurine nucleosides (1-4), a spiranic pyrimidone carbocyclic compound (5), and an unusual carbocyclic… 
1994
1994
Studies of inhibitor binding to Escherichia coli purine nucleoside phosphorylase using the transferred nuclear Overhauser effect and rotating-frame nuclear Overhauser enhancement.
NMR studies of the adenosine analog tubercidin have been carried out in the presence of Escherichia coli purine nucleoside… 
Review
1990
Review
1990
Future prospects for the chemotherapy of human trypanosomiasis. 2. Combination chemotherapy and African trypanosomiasis.
1990
1990
Purine nucleoside phosphorylase: purification using an ether-linked formycin B/sepharose 6B resin with unusual properties.
Formycin B [9-deazainosine] was reacted with epoxy-activated Sepharose 6B to form an affinity resin for purine nucleoside… 
1987
1987
Pneumocystis carinii pneumonia therapy with 9-deazainosine in rats.
1987
1987
Activity of purine analogs against Leishmania donovani in vivo
The dose of orally administered 9-deazainosine calculated to suppress 50% of Leishmania donovani amastigotes in hamster livers… 
1986
1986
Activity of inosine analogs against Pneumocystis carinii in culture
Three analogs of inosine, formycin B, allopurinol ribonucleoside, and 9-deazainosine, were tested for their ability to suppress… 
Highly Cited
1985
Highly Cited
1985
Inosine analogs. Their metabolism in mouse L cells and in Leishmania donovani.
1985
1985
Inosine analogs as chemotherapeutic agents for African trypanosomes: metabolism in trypanosomes and efficacy in tissue culture
Certain purine analogs, the pyrazolopyrimidines, are effective chemotherapeutic agents against Leishmania spp. and Trypanosoma… 
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