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9,10-Dimethyl-1,2-benzanthracene

Known as: 1,4-Dimethyl-2,3-benzphenanthrene, 7,12-dimentylbenzanthracene, 9,10-Dimethyl-1,2-benzanthracene [Chemical/Ingredient] 
A polycyclic aromatic hydrocarbon produced during combustion of fuels exhibiting carcinogenic activity. In addition, dimethylbenzanthracene is found… 
National Institutes of Health

Related topics

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17 relations

Narrower (8)

12-hydroxymethyl-7-methylbenz(a)anthracene5-fluoro-12-methylbenzanthryl-7-acetic acid7,11,12-trimethylbenz(a)anthracene7,12-dimethylbenz(a)anthracene-DNA adduct

Broader (2)

BenzanthracenesCarcinogens
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
1988
Highly Cited
1988
Ring-substituted [1,2-bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum (II) complexes: compounds with a selective effect on the hormone-dependent mammary carcinoma.
[1,2-Bis(4-hydroxyphenyl)ethylenediamine]dichloroplatinum (II) complexes with one substituent in the 2-position (CH3, CF3, F, Cl… 
Highly Cited
1984
Highly Cited
1984
Promotion of 7,12-dimethylbenz[a]anthracene-induced mammary tumorigenesis by high dietary fat in the rat: possible role of intercellular communication.
The effect of high levels of dietary fat on the promotion phase of rat mammary tumorigenesis and the effect of unsaturated and… 
Highly Cited
1983
Highly Cited
1983
Effect of the prostaglandin synthetase inhibitor indomethacin on 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats fed different levels of fat.
The effect of the prostaglandin synthetase inhibitor indomethacin on the dietary fat enhancement of 7,12-dimethylbenz(a… 
Highly Cited
1982
Highly Cited
1982
A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[alpha]anthracene.
7-Hydroxymethyl-12-methylbenz[alpha]anthracene (7-HMBA), a carcinogenic major metabolite of 7,12-dimethylbenz[alpha]anthracene… 
Highly Cited
1982
Highly Cited
1982
Differential effects of retinoic acid and 7,8-benzoflavone on the induction of mouse skin tumors by the complete carcinogenesis process and by the initiation-promotion regimen.
Abstract The present study was designed to elucidate differences in the mechanism of the induction of mouse skin tumors either by… 
Highly Cited
1982
Highly Cited
1982
Enhanced inhibition of mammary carcinogenesis by combined treatment with N-(4-hydroxyphenyl)retinamide and ovariectomy.
Bilateral ovariectomy and dietary administration of the retinoid N-(4-hydroxyphenyl)retinamide (4-HPR) are both effective… 
Highly Cited
1981
Highly Cited
1981
Comparison of two-stage epidermal carcinogenesis initiated by 7,12-dimethylbenz(a)anthracene or N-methyl-N'-nitro-N-nitrosoguanidine in newborn and adult SENCAR and BALB/c mice.
In order to define factors which determine susceptibility to chemical carcinogenesis, mice sensitive (SENCAR) and resistant (BALB… 
Highly Cited
1976
Highly Cited
1976
In vitro malignant transformation of mouse fibroblasts by non-K-region dihydrodiols derived from 7-methylbenz(a)anthracene, 7,12-dimethylbenz(a)anthracene, and benzo(a)pyrene.
The 8,9-dihydrodiols of 7-methylbenz(a)anthracene and 7,12-dimethylbenz(a)anthracene and the 7,8-dihydrodiol of benzo(a)pyrene… 
Highly Cited
1976
Highly Cited
1976
Importance of mammary gland DNA synthesis on carcinogen-induced mammary tumorigenesis in rats.
DNA synthesis in mammary gland estimated by [3H]thymidine incorporation was significantly higher on the day of proestrus than on… 
Highly Cited
1969
Highly Cited
1969
The effect of topical vitamin A on papillomas and intraepithelial carcinomas induced in hamster cheek pouches with 9,10-dimethyl-1,2-benzanthracene.
Summary Foci of intraepithelial carcinoma and benign papillomas up to 2 mm in diameter were present in the cheek pouches of all 6… 
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