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9,10-Dimethyl-1,2-benzanthracene

Known as: 1,4-Dimethyl-2,3-benzphenanthrene, 7,12-dimentylbenzanthracene, 9,10-Dimethyl-1,2-benzanthracene [Chemical/Ingredient] 
A polycyclic aromatic hydrocarbon produced during combustion of fuels exhibiting carcinogenic activity. In addition, dimethylbenzanthracene is found… 
National Institutes of Health

Related topics

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17 relations

Narrower (8)

12-hydroxymethyl-7-methylbenz(a)anthracene5-fluoro-12-methylbenzanthryl-7-acetic acid7,11,12-trimethylbenz(a)anthracene7,12-dimethylbenz(a)anthracene-DNA adduct

Broader (2)

BenzanthracenesCarcinogens
In Bloodagonistsanalogs & derivativesantagonists & inhibitors

Papers overview

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Highly Cited
2008
Highly Cited
2008
In vivo mutation assay based on the endogenous Pig‐a locus
The product of the X‐chromosome's Pig‐a gene acts in the first step of glycosylphosphatidylinositol (GPI) anchor biosynthesis… 
Highly Cited
2001
Highly Cited
2001
NAD(P)H:quinone oxidoreductase 1 deficiency and increased susceptibility to 7,12-dimethylbenz[a]-anthracene-induced carcinogenesis in mouse skin.
BACKGROUND The phase II enzyme NAD(P)H :quinone oxidoreductase 1 (NQO1) catalyzes quinone detoxification, protecting cells from… 
Highly Cited
1999
Highly Cited
1999
Cancer initiation by polycyclic aromatic hydrocarbons results from formation of stable DNA adducts rather than apurinic sites.
Polycyclic aromatic hydrocarbons (PAHs) are ubiquitous environmental pollutants with high carcinogenic potencies that have been… 
Highly Cited
1983
Highly Cited
1983
Effect of the prostaglandin synthetase inhibitor indomethacin on 7,12-dimethylbenz(a)anthracene-induced mammary tumorigenesis in rats fed different levels of fat.
The effect of the prostaglandin synthetase inhibitor indomethacin on the dietary fat enhancement of 7,12-dimethylbenz(a… 
Highly Cited
1982
Highly Cited
1982
A 7-hydroxymethyl sulfate ester as an active metabolite of 7,12-dimethylbenz[alpha]anthracene.
7-Hydroxymethyl-12-methylbenz[alpha]anthracene (7-HMBA), a carcinogenic major metabolite of 7,12-dimethylbenz[alpha]anthracene… 
Highly Cited
1980
Highly Cited
1980
Towards an improved micronucleus test: studies on 3 model agents, mitomycin C, cyclophosphamide and dimethylbenzanthracene.
Highly Cited
1977
Highly Cited
1977
The effects of antioxidants on skin tumor initiation and aryl hydrocarbon hydroxylase.
Butylated hydroxytoluene, butylated hydroxyanisole, and vitamins C and E are effective inhibitors of 7,12-dimethylbenz(a… 
Highly Cited
1977
Highly Cited
1977
Liver homogenate-mediated mutagenesis in chinese hamster V79 cells by polycyclic aromatic hydrocarbons and aflatoxins.
Highly Cited
1977
Highly Cited
1977
Inhibition of mammary cancer by retinyl methyl ether.
Daily feeding of the synthetic retinoid, retinyl methyl ether, beginning one week after the oral administration of 7,12… 
Highly Cited
1962
Highly Cited
1962
The role of ovarian hormones in initiating the induction of mammary cancer in rats by polynuclear hydrocarbons.
Summary The current studies demonstrate the critical importance of ovarian hormones in the initiation and promotion of… 
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