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8-chloroadenosine

Known as: 8-Chloro-adenosine, Adenosine, 8-Chloro-, 8-Cl-adenosine 
An antimetabolite and a chlorine derivative of the purine nucleoside adenosine, with potential antineoplastic activity. Upon administration, 8-chloro… 
National Institutes of Health

Papers overview

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2010
2010
In contrast to deoxyribose or arabinose containing nucleoside analogs that are currently established for cancer therapeutics, 8… 
1999
1999
Taxol is a unique anticancer agent that is used in treatment of advanced ovarian cancer. Taxol exposure results in the… 
1996
1996
BACKGROUND 8-Chloroadenosine 3',5'-monophosphate (8-Cl-cAMP) is undergoing phase I clinical trials as an anticancer drug. However… 
Highly Cited
1993
Highly Cited
1993
The 8-chloro analogue of the regulatory molecule, cyclic AMP (cAMP), modulates the intracellular concentrations of cAMP-dependent… 
1992
1992
Recent interest in site-selective cAMP analogs has focused on the role of 8-chloro-adenosine (8-Cl- adenosine) In the inhibition… 
1992
1992
The physiologic balance between the two regulatory subunit isoforms, RI and RII, of cAMP-dependent protein kinase is disrupted in…