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Pancreatic cancer is a highly aggressive malignancy and one of the leading causes of cancer deaths, mainly due to the lack of… Expand Background & aims: Pathogenesis of gastric cancer is driven by an accumulation of genetic changes that to a large extent occur at… Expand PON gene family includes at least three members termed PON1, PON2 and PON3, and it is mapped on human chromosome 7q21-q22. PON1… Expand Several independent genome scans have revealed excess allele sharing in an overlapping 40 cM region of 7q21‐34 in autism. DLX6… Expand The anti-atherogenic effect of HDL has been suggested to be partly due to the action of HDL-associated paraoxonase (PON). Three… Expand Breast cancer cell lines provide a useful starting point for the discovery and functional analysis of genes involved in breast… Expand Cerebral cavernous malformations (CCM) are congenital vascular anomalies of the brain that can cause significant neurological… Expand Defining the genetic determinants of NIDDM requires evidence from several complementary approaches, including both linkage and… Expand Split hand/split foot (SHFD) is a human developmental defect characterized by missing digits, fusion of remaining digits, and a… Expand Ectrodactyly is a genetically heterogeneous human limb developmental malformation with an autosomal locus at 7q21 designated… Expand