Skip to search formSkip to main content
You are currently offline. Some features of the site may not work correctly.

7-ethyl-10-hydroxycamptothecin glucuronide

Known as: SN-38 glucuronide 
 
National Institutes of Health

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2009
Highly Cited
2009
PURPOSE We aim to identify genetic variation, in addition to the UGT1A1*28 polymorphism, that can explain the variability in… Expand
  • figure 1
  • table 1
  • table 1
  • table 2
  • table 2
Is this relevant?
2008
2008
Irinotecan, a chemotherapeutic agent against various solid tumors, is a prodrug requiring activation to SN-38. Irinotecan's… Expand
Is this relevant?
2008
2008
The coadministration of protease inhibitors with anticancer drugs in the management of human immunodeficiency virus-related… Expand
Is this relevant?
2004
2004
This study was conducted to determine the maximum tolerated dose and dose-limiting toxicity of irinotecan (CPT-11) administered… Expand
  • table 1
  • table 2
  • table 3
  • table 4
  • table 4
Is this relevant?
Highly Cited
2002
Highly Cited
2002
The metabolism of irinotecan (CPT-11) involves sequential activation to SN-38 and detoxification to the pharmacologically… Expand
  • figure 1
  • table 1
  • figure 2
Is this relevant?
Highly Cited
2002
Highly Cited
2002
Irinotecan hydrochloride (CPT-11) is an anticancer agent with unpredictable bouts of diarrhea as a dose-limiting toxic side… Expand
Is this relevant?
2002
2002
OBJECTIVE The objective of the study was to develop and validate a population pharmacokinetic model for irinotecan and 2 of its… Expand
Is this relevant?
Highly Cited
1999
Highly Cited
1999
PURPOSE To determine the activity, toxicity, and pharmacokinetics of irinotecan (CPT-11, Camptosar; Pharmacia & Upjohn, Kalamazoo… Expand
Is this relevant?
1998
1998
PURPOSE In vitro synergy between cisplatin and irinotecan (CPT-11) has been reported. We designed a combination schedule of these… Expand
Is this relevant?
1996
1996
PURPOSE A pharmacokinetic study was performed during a phase II clinical trial of irinotecan (CPT-11) to confirm the… Expand
Is this relevant?