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7-ethyl-10-hydroxycamptothecin glucuronide

Known as: SN-38 glucuronide 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
The coadministration of protease inhibitors with anticancer drugs in the management of human immunodeficiency virus‐related… 
Highly Cited
2006
Highly Cited
2006
Pharmacogenetic testing for UDP‐glucuronosyltransferase (UGT) 1A1*28, a promoter variant of the UGT1A1 gene, is now carried out… 
Highly Cited
2005
Highly Cited
2005
Purpose: Ketoconazole has been shown to inhibit the glucuronidation of the UGT2B7 substrates zidovudine and lorazepam. Its effect… 
Highly Cited
2002
Highly Cited
2002
Abstract.Purpose: The extensive and unpredictable biliary excretion of CPT-11 and its metabolites, SN-38 and SN-38 glucuronide… 
2002
2002
Irinotecan or CPT-11 [7-ethyl-10-[4-(1-piperidino)-1-piperidino]carbonyloxycamptothecine] is a derivative of camptothecine used… 
Highly Cited
2000
Highly Cited
2000
This study determined the disposition of irinotecan hydrochloride trihydrate (CPT-11) after i.v. infusion of 125 mg/m(2) (100… 
Highly Cited
1998
Highly Cited
1998
PURPOSE In vitro synergy between cisplatin and irinotecan (CPT-11) has been reported. We designed a combination schedule of these… 
Highly Cited
1996
Highly Cited
1996
PURPOSE To construct limited-sampling models (LSMs) for irinotecan (CPT-11) pharmacokinetic (PK) measures. MATERIALS AND…