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7-deoxyadriamycin aglycone

Known as: doxorubicin 7-deoxyaglycone, 7-deoxydoxorubicinone, 7-deoxydoxorubicin aglycone 
 
National Institutes of Health

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Naphthacenes

Papers overview

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2010
2010
Tandem laser-induced fluorescence and mass spectrometry detection for high-performance liquid chromatography analysis of the in vitro metabolism of doxorubicin.
Structural characterization, identification, and quantification of xenobiotics and their metabolic products commonly require the… Expand
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2004
2004
Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma
PurposeSystemic chemotherapy is the treatment of choice for AIDS-related advanced Kaposi sarcoma. One principal schedule combines… Expand
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2004
2004
Subcellular metabolite profiles of the parent CCRF-CEM and the derived CEM/C2 cell lines after treatment with doxorubicin.
Micellar electrokinetic capillary chromatography with laser-induced fluorescence detection was used to detect the differences in… Expand
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2003
2003
Distribution of zeptomole-abundant doxorubicin metabolites in subcellular fractions by capillary electrophoresis with laser-induced fluorescence detection.
Doxorubicin (DOX) treatment of NS-1 mouse hybridoma cells results in the formation of zeptomole amounts of metabolites per cell… Expand
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1999
1999
Comparative effects of paclitaxel and docetaxel on the metabolism and pharmacokinetics of epirubicin in breast cancer patients.
PURPOSE To investigate whether paclitaxel and docetaxel influence the pharmacokinetics and metabolism of epirubicin. PATIENTS… Expand
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1998
1998
Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.
A sensitive and selective reversed-phase high-performance liquid chromatographic method for the quantification of doxorubicin and… Expand
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1995
1995
Distribution, Metabolism and Tumoricidal Activity of Doxorubicin Administered in Sorbitan Monostearate (Span 60) Niosomes in the Mouse
AbstractPurpose. Encapsulation of doxorubicin in niosomes was sought as a route to tumour targeting and improved tumoricidal… Expand
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1993
1993
A sensitive and simple high-performance liquid chromatographic method for the determination of doxorubicin and its metabolites in plasma.
A sensitive high-performance liquid chromatographic (HPLC) method for the measurement of doxorubicin and its metabolites in… Expand
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1991
1991
HPLC determination of doxorubicin, doxorubicinol and four aglycone metabolites in plasma of AIDS patients.
A high-performance liquid chromatographic (HPLC) assay has been developed for the determination of the anticancer drug… Expand
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1990
1990
Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer
SummaryRecombinant human granulocyte colony-stimulating factor (G-CSF) has been shown to reduce neutropenia following cytotoxic… Expand
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