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7-deoxyadriamycin aglycone

Known as: doxorubicin 7-deoxyaglycone, 7-deoxydoxorubicinone, 7-deoxydoxorubicin aglycone 
National Institutes of Health

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Naphthacenes

Papers overview

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2007
2007
Doxorubicin levels in the serum and ascites of patients with ovarian cancer.
2004
2004
Subcellular metabolite profiles of the parent CCRF-CEM and the derived CEM/C2 cell lines after treatment with doxorubicin.
2004
2004
Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer
SummaryRecombinant human granulocyte colony-stimulating factor (G-CSF) has been shown to reduce neutropenia following cytotoxic… 
2003
2003
Distribution of zeptomole-abundant doxorubicin metabolites in subcellular fractions by capillary electrophoresis with laser-induced fluorescence detection.
Doxorubicin (DOX) treatment of NS-1 mouse hybridoma cells results in the formation of zeptomole amounts of metabolites per cell… 
Highly Cited
1999
Highly Cited
1999
Comparative effects of paclitaxel and docetaxel on the metabolism and pharmacokinetics of epirubicin in breast cancer patients.
PURPOSE To investigate whether paclitaxel and docetaxel influence the pharmacokinetics and metabolism of epirubicin. PATIENTS… 
1995
1995
Pharmacokinetic drug interaction between epirubicin and interferon-alpha-2b in serum and red blood cells.
The influence of interferon-alpha-2b (CAS 99210-65-8, IFN) on the pharmacokinetics of epirubicin (CAS 56420-45-2, EPR) was… 
1994
1994
In vitro and in vivo Binding of Epirubicin to Red Blood Cells and Human Plasma Proteins
In this study, the in vitro interaction of epirubicin (EPR), a cytostatic antibiotic, with plasma proteins (PP), namely α-HSA… 
1986
1986
Analysis of doxorubicin, 4'-epidoxorubicin, and their metabolites by liquid chromatography.
An analytical method based on isocratic HPLC separation and fluorescence detection was developed to allow for sensitive and… 
1986
1986
Effect of hyperthermia on the in vitro metabolism of doxorubicin.
The effect of hyperthermia on the uptake and metabolism of doxorubicin (ADM) was studied in in vitro systems. ADM uptake in rat… 
1986
1986
Marked inter-patient variation in adriamycin biotransformation to 7-deoxyaglycones: evidence from metabolites identified in serum.
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