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7-deoxyadriamycin aglycone

Known as: doxorubicin 7-deoxyaglycone, 7-deoxydoxorubicinone, 7-deoxydoxorubicin aglycone 
National Institutes of Health

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Broader (1)

Naphthacenes

Papers overview

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Highly Cited
2004
Highly Cited
2004
Distribution, Metabolism and Tumoricidal Activity of Doxorubicin Administered in Sorbitan Monostearate (Span 60) Niosomes in the Mouse
AbstractPurpose. Encapsulation of doxorubicin in niosomes was sought as a route to tumour targeting and improved tumoricidal… 
2004
2004
Pharmacokinetics of low-dose doxorubicin and metabolites in patients with AIDS-related Kaposi sarcoma
PurposeSystemic chemotherapy is the treatment of choice for AIDS-related advanced Kaposi sarcoma. One principal schedule combines… 
2004
2004
Comparative pharmacokinetics of escalating doses of doxorubicin in patients with metastatic breast cancer
SummaryRecombinant human granulocyte colony-stimulating factor (G-CSF) has been shown to reduce neutropenia following cytotoxic… 
2003
2003
Distribution of zeptomole-abundant doxorubicin metabolites in subcellular fractions by capillary electrophoresis with laser-induced fluorescence detection.
Doxorubicin (DOX) treatment of NS-1 mouse hybridoma cells results in the formation of zeptomole amounts of metabolites per cell… 
Highly Cited
1999
Highly Cited
1999
Comparative effects of paclitaxel and docetaxel on the metabolism and pharmacokinetics of epirubicin in breast cancer patients.
PURPOSE To investigate whether paclitaxel and docetaxel influence the pharmacokinetics and metabolism of epirubicin. PATIENTS… 
Highly Cited
1998
Highly Cited
1998
Determination of doxorubicin and metabolites in murine specimens by high-performance liquid chromatography.
1996
1996
Determination of plasma concentrations of epirubicin and its metabolites by high-performance liquid chromatography during a 96-h infusion in cancer chemotherapy.
Highly Cited
1993
Highly Cited
1993
A Sensitive and Simple High‐Performance Liquid Chromatographic Method for the Determination of Doxorubicin and Its Metabolites in Plasma
A sensitive high-performance liquid chromatographic (HPLC) method for the measurement of doxorubicin and its metabolites in… 
1991
1991
HPLC determination of doxorubicin, doxorubicinol and four aglycone metabolites in plasma of AIDS patients.
1986
1986
Analysis of doxorubicin, 4'-epidoxorubicin, and their metabolites by liquid chromatography.
An analytical method based on isocratic HPLC separation and fluorescence detection was developed to allow for sensitive and… 
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