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7-deazaguanosine

Known as: 4H-Pyrrolo(2,3-d)pyrimidin-4-one, 2-amino-1,7-dihydro-7-beta-D-ribofuranosyl- 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Guanosine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
Highly Cited
2008
Highly Cited
2008
Biosynthesis of 7-Deazaguanosine-Modified tRNA Nucleosides: a New Role for GTP Cyclohydrolase I
ABSTRACT Queuosine (Q) and archaeosine (G+) are hypermodified ribonucleosides found in tRNA. Q is present in the anticodon region… 
Review
2008
Review
2008
An embarrassment of riches: the enzymology of RNA modification.
Highly Cited
2008
Highly Cited
2008
Modifications in Small Interfering RNA That Separate Immunostimulation from RNA Interference1
Synthetic small interfering RNA (siRNA) can suppress the expression of endogenous mRNA through RNA interference. It has been… 
Highly Cited
2004
Highly Cited
2004
Identification of Four Genes Necessary for Biosynthesis of the Modified Nucleoside Queuosine*
Queuosine (Q) is a hypermodified 7-deazaguanosine nucleoside located in the anticodon wobble position of four amino acid-specific… 
Highly Cited
2003
Highly Cited
2003
Molecular basis for the immunostimulatory activity of guanine nucleoside analogs: Activation of Toll-like receptor 7
Certain C8-substituted and N7, C8-disubstituted guanine ribonucleosides comprise a class of small molecules with… 
Review
2003
Review
2003
Biosynthesis of the 7-deazaguanosine hypermodified nucleosides of transfer RNA.
Highly Cited
1997
Highly Cited
1997
Biosynthesis of Archaeosine, a Novel Derivative of 7-Deazaguanosine Specific to Archaeal tRNA, Proceeds via a Pathway Involving Base Replacement on the tRNA Polynucleotide Chain*
Archaeosine is a novel derivative of 7-deazaguanosine found in transfer RNAs of most organisms exclusively in the archaeal… 
Highly Cited
1997
Highly Cited
1997
Formation of a G-tetrad and higher order structures correlates with biological activity of the RelA (NF-kappaB p65) 'antisense' oligodeoxynucleotide
We have examined the behavior of the phosphorothioate antisense Rel A (NF-kappaB p65) oligodeoxynucleotide (oligo) and related… 
1991
1991
Immunoenhancing properties and antiviral activity of 7-deazaguanosine in mice
The nucleotide analog 7-deazaguanosine has not previously been reported to possess biological (antiviral or antitumor) properties… 
Highly Cited
1975
Highly Cited
1975
Structure of the modified nucleoside Q isolated from Escherichia coli transfer ribonucleic acid. 7-(4,5-cis-Dihydroxy-1-cyclopenten-3-ylaminomethyl)-7-deazaguanosine.
The structure of the unknown modified nucleoside Q, which is present in the first position of the anticodons of Escherichia coli… 
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