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7-deaza-R34

Known as: hammerhead ribozyme 7-deaza-R34 
National Institutes of Health

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1 relation

Broader (1)

Catalytic RNA

Papers overview

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2018
2018
Structural Simplicity and Mechanistic Complexity in the Hammerhead Ribozyme.
2014
2014
Improved design of hammerhead ribozyme for selective digestion of target RNA through recognition of site-specific adenosine-to-inosine RNA editing
Adenosine-to-inosine RNA editing is an endogenous mechanism for regulating various biological processes. A method for site… 
Review
2010
Review
2010
What can the New Hammerhead Ribozyme Structures Teach us About Design
The hammerhead ribozyme is a small, self-cleaving genomic ribozyme whose substrate-targeting properties are quite flexible. It… 
2009
2009
Efficient control of group I intron ribozyme catalysis by DNA constraints.
Double-stranded DNA constraints enable efficient control of catalysis by a large multi-domain group I intron ribozyme. 
2007
2007
The tolerance to exchanges of the Watson Crick base pair in the hammerhead ribozyme core is determined by surrounding elements.
Tertiary interacting elements are important features of functional RNA molecules, for example, in all small nucleolytic ribozymes… 
2007
2007
Hammerhead ribozyme-based target discovery.
With the accumulation of vast amounts of data as a result of the sequencing of the human genome, it is necessary to identify… 
2003
2003
Solvent protection of the hammerhead ribozyme in the ground state: evidence for a cation-assisted conformational change leading to catalysis.
Tertiary folding of the hammerhead ribozyme has been analyzed by hydroxyl radical footprinting. Three hammerhead constructs with… 
2000
2000
Multiple conformational states of the hammerhead ribozyme, broad time range of relaxation and topology of dynamics.
The dynamics of a hammerhead ribozyme was analyzed by measurements of fluorescence-detected temperature jump relaxation. The… 
2000
2000
Significant activity of a modified ribozyme with N7‐deazaguanine at G10.1: the double‐metal‐ion mechanism of catalysis in reactions catalysed by hammerhead ribozymes
Several reports have appeared recently of experimental evidence for a double‐metal‐ion mechanism of catalysis in reactions… 
1997
1997
Relating conformation, Mg2+ binding, and functional group modification in the hammerhead ribozyme.
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