7-deaza-2'-deoxyguanosine

CpG DNA induces potent Th1 immune responses through Toll-like receptor 9. In the present study, we used oligonucleotides… Expand

OBJECTIVES PCR has become a routine technique in DNA genotyping for diagnostic or pharmacogenetics purposes. Promoter regions of… Expand

CpG islands are GC rich sequences that are found in the promoters of many genes in higher eukaryotes. They contain a high… Expand

The synthesis, hybridization properties and antisense activities of oligodeoxynucleotides (ODNs) containing 7-(1-propynyl)-7… Expand

Phylogenetically invariant G.U wobble pairs are present in a wide variety of RNA's. As a means to study the contribution of… Expand

Triple helix formation of oligodeoxynucleotides (ODNs) with a 15 base pair poly-purine DNA target in the HER2 promoter was… Expand

In order to investigate the possible importance of Hoogsteen base pairing to the DNA-binding ability of echinomycin, quantitative… Expand

The synthesis of alternating hexamers (8-13) derived from d(C-G)3 or d(G-C)3 but containing c7z8Gd (2) or c7Gd (3) instead of dG… Expand

The highly thermostable DNA polymerase from Thermus aquaticus (Taq) is ideal for both manual and automated DNA sequencing because… Expand