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7-deaza-2'-deoxyguanosine

Known as: 2'-deoxy-7-deazaguanosine 
 
National Institutes of Health

Related topics

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2 relations

Broader (1)

Deoxyguanosine
analogs & derivatives

Papers overview

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Highly Cited
2003
Highly Cited
2003
Divergent synthetic nucleotide motif recognition pattern: design and development of potent immunomodulatory oligodeoxyribonucleotide agents with distinct cytokine induction profiles.
Unmethylated CpG dinucleotides present within certain specific sequence contexts in bacterial and synthetic DNA stimulate innate… Expand
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2002
2002
7-Deaza-2`-deoxyguanosine allows PCR and sequencing reactions from CpG islands
CpG islands are GC rich sequences that are found in the promoters of many genes in higher eukaryotes. They contain a high… Expand
Highly Cited
1996
Highly Cited
1996
Oligodeoxynucleotides containing C-7 propyne analogs of 7-deaza-2'-deoxyguanosine and 7-deaza-2'-deoxyadenosine.
The synthesis, hybridization properties and antisense activities of oligodeoxynucleotides (ODNs) containing 7-(1-propynyl)-7… Expand
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Highly Cited
1994
Highly Cited
1994
The 2,6-diaminopurine riboside.5-methylisocytidine wobble base pair: an isoenergetic substitution for the study of G.U pairs in RNA.
Phylogenetically invariant G.U wobble pairs are present in a wide variety of RNA's. As a means to study the contribution of… Expand
Highly Cited
1993
Highly Cited
1993
An anti-parallel triple helix motif with oligodeoxynucleotides containing 2'-deoxyguanosine and 7-deaza-2'-deoxyxanthosine.
Triple helix formation of oligodeoxynucleotides (ODNs) with a 15 base pair poly-purine DNA target in the HER2 promoter was… Expand
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1989
1989
Alternating d(G-C)3 and d(C-G)3 hexanucleotides containing 7-deaza-2'-deoxyguanosine or 8-aza-7-deaza-2'-deoxyguanosine in place of dG.
The synthesis of alternating hexamers (8-13) derived from d(C-G)3 or d(G-C)3 but containing c7z8Gd (2) or c7Gd (3) instead of dG… Expand
Highly Cited
1988
Highly Cited
1988
DNA sequencing with Thermus aquaticus DNA polymerase and direct sequencing of polymerase chain reaction-amplified DNA.
The highly thermostable DNA polymerase from Thermus aquaticus (Taq) is ideal for both manual and automated DNA sequencing because… Expand
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Highly Cited
1988
Highly Cited
1988
Structure-independent DNA amplification by PCR using 7-deaza-2'-deoxyguanosine.
 
Highly Cited
1986
Highly Cited
1986
Palindromic oligonucleotides containing 7-deaza-2'-deoxyguanosine: solid-phase synthesis of d[(p)GG*AATTCC] octamers and recognition by the endodeoxyribonuclease EcoRI.
Octadeoxynucleotides with the sequence d[(p)GG*AATTCC] have been prepared by solid-phase synthesis employing regular and base… Expand
1985
1985
Solid-phase synthesis of the self-complementary hexamer d(c7GpCpc7GpCpc7GpC) via the O-3'-phosphoramidite of 7-deaza-2'-deoxyguanosine.
The synthesis of the O-3'-phosphoramidite of a suitably protected 7-deaza-2'-deoxyguanosine (c7G) which is an isostere of 2… Expand
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