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6-pyruvoyltetrahydropterin synthase activity
Known as:
PTPS activity
, 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate lyase activity
, 2-amino-4-oxo-6-[(1S,2R)-1,2-dihydroxy-3-triphosphooxypropyl]-7,8-dihydroxypteridine triphosphate-lyase (6-pyruvoyl-5,6,7,8-tetrahydropterin-forming)
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Catalysis of the reaction: 7,8-dihydroneopterin 3'-triphosphate = 6-pyruvoyl-5,6,7,8-tetrahydropterin + H(+) + triphosphate. [EC:4.2.3.12, RHEA:22051…
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National Institutes of Health
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6-pyruvoyltetrahydropterin synthase
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
2014
2014
Structural basis of a novel activity of bacterial 6-pyruvoyltetrahydropterin synthase homologues distinct from mammalian 6-pyruvoyltetrahydropterin synthase activity.
K. Seo
,
N. Zhuang
,
Young Shik Park
,
K. Park
,
Kon-Ho Lee
Acta Crystallographica Section D: Biological…
2014
Corpus ID: 32795191
Escherichia coli 6-carboxytetrahydropterin synthase (eCTPS), a homologue of 6-pyruvoyltetrahydropterin synthase (PTPS), possesses…
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1998
1998
Regulation of 6-pyruvoyltetrahydropterin synthase activity and messenger RNA abundance in human vascular endothelial cells.
P. Linscheid
,
A. Schaffner
,
N. Blau
,
G. Schoedon
Circulation
1998
Corpus ID: 6696266
BACKGROUND The nitric oxide synthase cofactor tetrahydrobiopterin (BH4) is involved in the regulation of endothelium-dependent…
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1996
1996
Tetrahydrobiopterin induced neonatal tyrosinaemia
N. Blau
,
M. Beck
,
D. Matern
European Journal of Pediatrics
1996
Corpus ID: 26845552
Sir: Transient neonatal tyrosinaemia is thought to be caused by late maturation of the hepatic enzymes 4-hydroxyphenylpyruvate…
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Review
1991
Review
1991
Biochemistry and function of pteridine synthesis in human and murine macrophages.
E. Werner
,
G. Werner-Felmayer
,
+4 authors
H. Wachter
Pathobiology (Basel)
1991
Corpus ID: 46748551
We investigated intracellular pteridine concentrations, activities of pteridine biosynthetic enzymes and formation of nitrogen…
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