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6-methylthioguanine

Known as: S6-methylthioguanine 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

Thioguanine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2012
2012
Effects of 6-Thioguanine and S6-Methylthioguanine on Transcription in Vitro and in Human Cells*
Background: Thiopurine prodrugs can result in the formation of S6-methylthioguanine (S6mG) and 6-thioguanine (SG) in DNA. Results… 
2011
2011
Quantification of Thiopurine/UVA-Induced Singlet Oxygen Production.
2011
2011
Preclinical evaluation of azathioprine plus buthionine sulfoximine in the treatment of human hepatocarcinoma and colon carcinoma.
AIM To evaluate the efficacy and the safety of azathioprine (AZA) and buthionine sulfoximine (BSO) by localized application into… 
2010
2010
LC-MS/MS coupled with stable isotope dilution method for the quantification of 6-thioguanine and S(6)-methylthioguanine in genomic DNA of human cancer cells treated with 6-thioguanine.
Thiopurines, including mercaptopurine (MP), 6-thioguanine ((S)G) and azathioprine, are widely used for the treatment of many… 
Highly Cited
2008
Highly Cited
2008
Ethnic variation of thiopurine S-methyltransferase activity: a large, prospective population study.
UNLABELLED The use of azathioprine (and its metabolite mercaptopurine) is limited by toxicity, especially myelosuppression, which… 
2006
2006
The syntheses and properties of tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine and O6-methylguanine.
The syntheses of novel tricyclic pyrrolo[2,3-d]pyrimidine analogues of S6-methylthioguanine are described. The crystal structures… 
2003
2003
Determination of thiopurine S-methyltransferase activity in erythrocytes using 6-thioguanine as substrate and a non-extraction liquid chromatographic technique.
  • L. FordJ. Berg
  • Journal of chromatography. B, Analytical…
  • 2003
  • Corpus ID: 45616702
1998
1998
High-performance liquid chromatographic assay of methylthioguanine nucleotide.
Highly Cited
1986
Highly Cited
1986
Inactivation of O6-methylguanine-DNA methyltransferase and sensitization of human tumor cells to killing by chloroethylnitrosourea by O6-methylguanine as a free base.
Human fibroblasts and tumor cells with constitutive levels of the DNA repair protein O6-methylguanine-DNA methyltransferase were… 
1977
1977
The quantitative determination of metabolites of 6-mercaptopurine in biological materials. I. A separation method for purine and 6-thiopurine bases and nucleosides using high-pressure liquid cation…
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