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6-codeinone

Known as: codeinone 
National Institutes of Health

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2 relations

Broader (1)

Codeine
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2007
2007
Live Cell Monitoring of μ-Opioid Receptor-mediated G-protein Activation Reveals Strong Biological Activity of Close Morphine Biosynthetic Precursors*
G-protein activation by receptors is generally measured using 35S-GTPγS binding assays in cell membranes and cannot be well… 
2005
2005
Effect of anticancer agents on codeinone-induced apoptosis in human cancer cell lines.
The possible apoptosis-inducing activity of codeinone, an oxidative metabolite of codeine, without or with anticancer drugs, was… 
Highly Cited
2003
Highly Cited
2003
Electrospray tandem mass spectrometric investigations of morphinans
2003
2003
The toxicity of opiates and their metabolites in HepG2 cells.
2002
2002
Alkaloid profiles of the Indian land races of the opiumpoppy Papaver somniferum L.
The capsule husks of a set of 115 Indian land races of opium poppy Papaver somniferum L. obtained over two cropping seasons were… 
1998
1998
Reductive and oxidative half-reactions of morphinone reductase from Pseudomonas putida M10: a kinetic and thermodynamic analysis.
The reaction of morphinone reductase (MR) with the physiological reductant NADH and the oxidizing substrate codeinone has been… 
1985
1985
Analgesics of the 6,14-ethenomorphinan type. 6-deoxy-7 alpha-orvinols and 6-deoxy-8 alpha-orvinols.
6-Deoxythebaine (3) has been prepared as a precursor to C-6 alkyl substituted orvinols 15 and 17. The C-6 methyl group was… 
1976
1976
A practical synthesis of codeine from dihydrothebainone.
The conversion of dihydrothebainone to codeine or thebaine has been achieved in high yield. Bromination and dehydrobromination… 
1976
1976
Conversion of Thebaine to Codeine.
An improved conversion of thebaine to codeine has been developed. Oxymercuration of thebaine with mercuric acetate in refluxing… 
1967
1967
Codeinone as the intermediate in the biosynthetic conversion of thebaine to codeine.
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