• Publications
  • Influence
Aerobic Degradation of 2,4,6-Trinitrotoluene byEnterobacter cloacae PB2 and by Pentaerythritol Tetranitrate Reductase
TLDR
The ability to remove nitrogen from TNT suggests that PB2 or recombinant organisms expressing PETN reductase may be useful for bioremediation of TNT-contaminated soil and water. Expand
Cloning, Sequencing, and Characterization of the Hexahydro-1,3,5-Trinitro-1,3,5-Triazine Degradation Gene Cluster from Rhodococcus rhodochrous
TLDR
This study is the first to present a gene which has been identified as being responsible for RDX biodegradation, and the mechanism of action of XplA on RDX is thought to involve initial denitration followed by spontaneous ring cleavage and mineralization. Expand
'New uses for an Old Enzyme'--the Old Yellow Enzyme family of flavoenzymes.
TLDR
After 60 years in isolation, the yeast Old Yellow Enzyme has become the archetype of a growing family of flavoenzymes that have been discovered through studies of bacterial metabolism and genome sequencing projects. Expand
Exploring the biochemical properties and remediation applications of the unusual explosive-degrading P450 system XplA/B
TLDR
Transgenic Arabidopsis plants expressing both xplA and xplB were generated, demonstrating the applicability of this system for the phytoremediation of RDX-contaminated sites and the presence of oxygen determines the final products ofRDX degradation. Expand
Degradation of hexahydro-1,3,5-trinitro-1,3,5-triazine (RDX) by Stenotrophomonas maltophilia PB1.
TLDR
A mixed microbial culture capable of metabolizing the explosive RDX was obtained from soil enrichments under aerobic and nitrogen-limiting conditions, yielding a metabolite identified by mass spectroscopy and 1H nuclear magnetic resonance analysis as methylene-N-(hydroxymethyl)-hydroxylamine-N'-(hydroxylethyl)nitroamin e.g. Expand
Detoxification of the explosive 2,4,6-trinitrotoluene in Arabidopsis: discovery of bifunctional O- and C-glucosyltransferases.
TLDR
The results show that UGTs play an integral role in the biochemical mechanism of TNT detoxification by plants, and are identified in extracts and media from Arabidopsis plants grown in liquid culture containing TNT. Expand
Lignocellulose degradation mechanisms across the Tree of Life
TLDR
The omics revolution is identifying many novel enzymes and paradigms for biomass deconstruction, but more emphasis on function is required, particularly for enzyme cocktails, in which LPMOs may play an important role. Expand
Biodegradation of explosives by transgenic plants expressing pentaerythritol tetranitrate reductase
TLDR
Transgenic tobacco plants expressing pentaerythritol tetranitrate reductase, an enzyme derived from an explosive-degrading bacterium that enables degradation of nitrate ester and nitroaromatic explosives, suggest that transgenic plants expressing microbial degradative genes may provide a generally applicable strategy for bioremediation of organic pollutants in soil. Expand
Biotransformation of Explosives by the Old Yellow Enzyme Family of Flavoproteins
TLDR
The findings suggest two distinct pathways of TNT transformation, with the initial reduction of TNT being the key point of difference between the enzymes. Expand
Phytoremediation of Explosives
TLDR
Phytoremediation has emerged as a focus for explosives remediation because of its low cost, low energy requirements, and promising research observing explosives removal from contaminated groundwater and soil. Expand
...
1
2
3
4
5
...