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5-oxoprolinase (ATP-hydrolysing) activity

Known as: 5-oxo-L-prolinase activity, 5-oxo-L-proline amidohydrolase (ATP-hydrolysing), oxoprolinase activity 
Catalysis of the reaction: 5-oxo-L-proline + ATP + 2 H(2)O = L-glutamate + ADP + 2 H(+) + phosphate. [EC:3.5.2.9, RHEA:10351]
National Institutes of Health

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Related topics

1 relation
OPLAH gene

Papers overview

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Highly Cited
1999
Highly Cited
1999
Purification and biochemical characteristics of β‐D‐xylanase from a thermophilic fungus, Thermomyces lanuginosus‐SSBP
An extracellular xylanase was purified to homogeneity from the culture filtrate of a thermophilic fungus, Thermomyces lanuginosus… 
Highly Cited
1999
Highly Cited
1999
Pancreatic lipase/colipase-mediated triacylglycerol hydrolysis is required for cholesterol transport from lipid emulsions to intestinal cells.
This study tested the hypothesis that dietary cholesterol uptake by intestinal cells is dependent on the structure and… 
Highly Cited
1988
Highly Cited
1988
Tissue-specific regulation of pyroglutamate aminopeptidase II activity by thyroid hormones.
Among the enzymes capable of degrading thyrotropin-releasing hormone (TRH) in vitro, two pyroglutamate aminopeptidases (PGA) are… 
1982
1982
New substrates of 5-oxo-L-prolinase.
Highly Cited
1981
Highly Cited
1981
Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate, a 5-oxo-L-prolinase substrate.
5-Oxo-L-prolinase, the enzyme that catalyzes the conversion of 5-oxo-L-proline to L-glutamate coupled to the cleavage of ATP to… 
Highly Cited
1979
Highly Cited
1979
Characterization of a thyroliberin-degrading serum enzyme catalyzing the hydrolysis of thyroliberin at the pyroglutamyl-histidine bond.
The enzymatic hydrolysis of thyroliberin (< Glu-His-Pro-NH2) by serum enzymes can be preferentially inhibited by 1 mM… 
1975
1975
5-Oxo-L-prolinase (L-pyroglutamate hydrolase). Purification and catalytic properties.
Highly Cited
1974
Highly Cited
1974
PYROGLUTAMIC ACIDURIA Studies in an Infant with Chronic Metabolic Acidosis
A one‐year‐old girl with chronic metabolic acidosis was found to have normal renal acidi‐fication. In the urine, however, she… 
Highly Cited
1964
Highly Cited
1964
Properties of the Penicillin Deacylase Enzyme of Escherichia coli
THE microbial enzyme which hydrolyses the side-chain from a penicillin to give 6-aminopenicillanic acid (6-APA) and carboxylic… 
Highly Cited
1954
Highly Cited
1954
The Use of a Bile-Aesculin Medium and of Maxted's Technique of Lancefield Grouping in the Identification of Enterococci (Group D Streptococci)
The name enterococcus, originally given by Thiercelin (1899) to a Gram-positive coccus of faecal origin growing in pairs and… 
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