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5-hydroxymethylomeprazole

Known as: 5-hydroxy omeprazole, 5-methoxy-2-(((4-methoxy-3-methyl-5-hydroxymethyl-2-pyridinyl)methyl)sulfinyl)-1H-benzimidazole, hydroxyomeprazole 
 
National Institutes of Health

Papers overview

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Highly Cited
2008
Highly Cited
2008
WHAT IS ALREADY KNOWN ABOUT THIS SUBJECT The only existing study of CYP2C19*17-associated alterations in drug pharmacokinetics… Expand
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2003
2003
Omeprazole has been used as a drug probe for CYP2C19, but no systematic data are available for Mexican populations. The aim of… Expand
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2000
2000
BACKGROUND Although it is known that the use of oral contraceptives inhibits oxidative drug metabolism, there is little… Expand
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1998
1998
OBJECTIVE This study investigated whether time-dependent artemisinin pharmacokinetics correlated to CYP3A4 or CYP2C19 activity in… Expand
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1998
1998
OBJECTIVE To investigate the CYP2C19 polymorphism in Tanzanians because this enzyme shows large interindividual differences in… Expand
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Highly Cited
1995
Highly Cited
1995
A single oral dose of omeprazole (20 mg) was given orally to 160 healthy Caucasian Swedish subjects and tested as a probe for… Expand
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Highly Cited
1995
Highly Cited
1995
1. Fourteen healthy Swedish Caucasian subjects were given 20 mg of omeprazole orally each morning for 8 days. The subjects… Expand
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Highly Cited
1994
Highly Cited
1994
1. The in vitro metabolism of omeprazole was studied in human liver microsomes in order to define the secondary metabolic… Expand
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Highly Cited
1993
Highly Cited
1993
1 The in vitro metabolism of omeprazole was studied in human liver microsomes in order to define the metabolic pathways and… Expand
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Highly Cited
1992
Highly Cited
1992
Twelve Caucasian healthy men and women, of whom six were poor metabolizers (PMs) and six were extensive metabolizers (EMs) of S… Expand
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