5-hydroxydiclofenac

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1996-2017
02419962017

Papers overview

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2012
2012
Diclofenac (DCF), a nonsteroidal anti-inflammatory drug, is well known to induce idiosyncratic hepatotoxicity. Although there… (More)
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2011
2011
Diclofenac is a widely used drug that can cause serious hepatotoxicity, which has been linked to metabolism by cytochrome P450s… (More)
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2010
2010
Diclofenac is an important analgesic and anti-inflammatory drug that is widely used for the treatment of postoperative pain… (More)
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2010
2010
The non-steroidal anti-inflammatory drugs diclofenac (DCF) and mefenamic acid (MFA) were treated with the white rot fungus… (More)
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2008
2008
Ozonation of diclofenac in aqueous solution in the presence and absence of an *OH scavenger, tertiary butanol (t-BuOH), was… (More)
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2006
2006
A rapid and sensitive high-performance liquid chromatographic method was developed for determination of diclofenac and its major… (More)
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Highly Cited
1999
Highly Cited
1999
Cytochrome P450 2C11 in rats was recently found to metabolize diclofenac into a highly reactive product that covalently bound to… (More)
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Highly Cited
1999
Highly Cited
1999
Diclofenac, a 2-arylacetic acid, nonsteroidal anti-inflammatory drug, has been reported to cause adverse hepatic effects in… (More)
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Highly Cited
1999
Highly Cited
1999
The aim of this study was to re-examine the human hepatic metabolism of diclofenac, with special focus on the generation of minor… (More)
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1999
1999
The cytochrome P-450 (CYP)3A4-mediated metabolism of diclofenac is stimulated in vitro by quinidine. A similar effect is observed… (More)
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