5-hydroxydiclofenac
National Institutes of Health
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To investigate the respective roles of cytochromes P450 2C9 and 3A in drug oxidation in human livers, the in vivo…
Diclofenac is a widely used drug that can cause serious hepatotoxicity, which has been linked to metabolism by cytochrome P450s…
Diclofenac is an important analgesic and anti-inflammatory drug that is widely used for the treatment of postoperative pain…
It has been known that diclofenac is biotransformed into chemically reactive metabolites, which bind covalently to liver…