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  • M. Waalkes
  • Medicine
  • Mutation research
  • 2003
  • Cadmium is a heavy metal of considerable environmental and occupational concern. Cadmium compounds are classified as human carcinogens by several regulatory agencies. The most convincing data thatExpand
  • C. Q. Zhao, M. R. Young, B. Diwan, T. Coogan, M. Waalkes
  • Medicine, Biology
  • Proceedings of the National Academy of Sciences…
  • 1997 (First Publication: 30 September 1997)
  • Inorganic arsenic, a human carcinogen, is enzymatically methylated for detoxication, consuming S-adenosyl-methionine (SAM) in the process. The fact that DNA methyltransferases (MeTases) require thisExpand
  • M. Takiguchi, W. Achanzar, W. Qu, G. Li, M. Waalkes
  • Biology, Medicine
  • Experimental cell research
  • 2003 (First Publication: 1 June 2003)
  • Cadmium is a human carcinogen that likely acts via epigenetic mechanisms. Since DNA methylation alterations represent an important epigenetic event linked to cancer, the effect of cadmium on DNAExpand
  • H. Chen, Shuanfang Li, Jie Liu, B. Diwan, J. Barrett, M. Waalkes
  • Biology, Medicine
  • Carcinogenesis
  • 2004 (First Publication: 1 April 2004)
  • Inorganic arsenic is a human carcinogen that can target the liver, but its carcinogenic mechanisms are still unknown. Global DNA hypomethylation occurs during arsenic-induced malignant transformationExpand
  • M. Waalkes
  • Chemistry, Medicine
  • Journal of inorganic biochemistry
  • 2000 (First Publication: 1 April 2000)
  • Cadmium is an inorganic toxicant of great environmental and occupational concern which was classified as a human carcinogen in 1993. Occupational cadmium exposure is associated with lung cancer inExpand