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5-fluorouridine 5'-triphosphate
Papers overview
Semantic Scholar uses AI to extract papers important to this topic.
Review
2018
Review
2018
Fluoropyrimidines such as 5-fluorouracil (5-FU) form the foundation of a wide variety of chemotherapy regimens. 5-FU is in fact… Expand
Highly Cited
1996
Highly Cited
1996
The mechanism of resistance to 5‐fluorouracil (5‐FU) was studied with NUGC‐3/5FU/L, a human stomach cancer cell line which had… Expand
Highly Cited
1995
Highly Cited
1995
Interferon-α (IFNα) potentiates the antitumor activity of 5-fluorouracil (FUra) in colon cancer in vitro, in vivo, and clinically… Expand
Highly Cited
1992
Highly Cited
1992
Interferon-alpha (IFN alpha) increases the cytotoxicity of 5-fluorouracil (FUra) in vitro, and the combination has clinical… Expand
Review
1991
Review
1991
Biochemical pharmacology and analysis of fluoropyrimidines alone and in combination with modulators.
After more than three decades since their introduction, fluoropyrimidines, especially FUra, are still a mainstay in the treatment… Expand
Review
1990
Review
1990
This is a review on the mechanism of action of FUra. Three main areas are addressed: metabolism, RNA-directed actions of FUra… Expand
Highly Cited
1989
Highly Cited
1989
19F-magnetic resonance spectroscopy (MRS) can be used to non-invasively monitor metabolism of 5-fluorouracil (5FU) to cytotoxic… Expand
Highly Cited
1988
Highly Cited
1988
We are interested in determining whether incorporation of the drug 5-fluorouracil into pre-mRNA can alter RNA processing. The… Expand
Highly Cited
1981
Highly Cited
1981
The intracellular metabolism of a new fluoropyrimidine, 5'-deoxy-5-fluorouridine (5'-dFUrd), was compared with the metabolism of… Expand
Highly Cited
1980
Highly Cited
1980
5'-Deoxy-5-fluorouridine (5'-dFUrd; Roche 21-9738) is a recently synthesized antineoplastic agent with therapeutic potential. The… Expand