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5-deazafolate

 
National Institutes of Health

Papers overview

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2007
2007
The synthesis of suitably protected p-aminophenyl H-phosphinic acids and esters from the corresponding para-substituted aryl… Expand
1999
1999
Rotationally restricted analogues of 5-deazapteroyl-L-glutamate and (6R,6S)-5-deaza-5,6,7,8-tetrahydropteroyl-L-glutamate with a… Expand
Highly Cited
1995
Highly Cited
1995
Crystal structures of Escherichia coli dihydrofolate reductase (ecDHFR, EC 1.5.1.3) in binary complexes with folate, 5… Expand
1992
1992
5-Deazafolate and 5-deazatetrahydrofolate (DATHF) analogues with the glutamic acid side chain replaced by homocysteic acid (HCysA… Expand
1992
1992
The kinetics of the NADPH-dependent reduction of 7,8-dihydrofolate, folate, and 7,8-dihydrobiopterin by human dihydrofolate… Expand
1991
1991
A remarkable correlation has been discovered between fluorescence lifetimes of bound NADPH and rates of hydride transfer among… Expand
Highly Cited
1990
Highly Cited
1990
The 2.3-A crystal structure of recombinant human dihydrofolate reductase (EC 1.5.1.3, DHFR) has been solved as a binary complex… Expand
1984
1984
The inhibition of dihydrofolate reductases from Escherichia coli and chicken liver by folate, methotrexate, aminopterin and their… Expand