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5,10-methylenetetrahydrofolate

Known as: 5,10 methylenetetrahydrofolate, MTHF, FOLITIXORIN 
A folate-based biomodulator with potential antineoplastic activity. 5,10-methylenetetrahydrofolate (MTHF) stabilizes the covalent binding of the… 
National Institutes of Health

Related topics

Related topics

4 relations

Broader (2)

5,10-methylenetetrahydrofolic acidFolacin

Narrower (1)

CoFactor brand of 5,10-methylenetetrahydrofolate
NCIt Antineoplastic Agent Terminology

Papers overview

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Highly Cited
2019
Highly Cited
2019
Aggregation‐Induced Multilength Scaled Morphology Enabling 11.76% Efficiency in All‐Polymer Solar Cells Using Printing Fabrication
All‐polymer solar cells (all‐PSCs) exhibit excellent stability and readily tunable ink viscosity, and are therefore especially… 
Highly Cited
2000
Highly Cited
2000
Production of levulinic acid and use as a platform chemical for derived products
Highly Cited
2000
Highly Cited
2000
Folic acid reverts dysfunction of endothelial nitric oxide synthase.
5-methyltetrahydrofolate (MTHF), the active form of folic acid, has been reported to restore NO status in hypercholesterolemic… 
Highly Cited
1995
Highly Cited
1995
Thermolabile 5,10-methylenetetrahydrofolate reductase as a cause of mild hyperhomocysteinemia.
Thermolability of 5,10-methylenetetrahydrofolate reductase (MTHFR) was examined as a possible cause of mild hyperhomocysteinemia… 
Highly Cited
1995
Highly Cited
1995
Crystal structure of DNA photolyase from Escherichia coli.
Photolyase repairs ultraviolet (UV) damage to DNA by splitting the cyclobutane ring of the major UV photoproduct, the cis, syn… 
Highly Cited
1995
Highly Cited
1995
A genetic defect in 5,10 methylenetetrahydrofolate reductase in neural tube defects.
It is now well-established that folic acid, taken peri-conceptionally, can reduce the risk of neural tube defects (NTDs). Recent… 
Highly Cited
1991
Highly Cited
1991
Does Hypogonadism Contribute to the Occurrence of a Minimal Trauma Hip Fracture in Elderly Men?
The risk of MTHF in hypogonadal elderly men was investigated with a case‐control model. Cases and controls were selected from… 
Highly Cited
1988
Highly Cited
1988
Intermediate homocysteinemia: a thermolabile variant of methylenetetrahydrofolate reductase.
A "newly detected" variant of methylenetetrahydrofolate (MTHF) reductase (E.C.1.1.1.68) deficiency associated with an 8-15-fold… 
Highly Cited
1988
Highly Cited
1988
Amino acid changes linked to pyrimethamine resistance in the dihydrofolate reductase-thymidylate synthase gene of Plasmodium falciparum.
We describe the isolation and the sequence of the gene for the bifunctional enzyme dihydrofolate reductase-thymidylate synthase… 
Highly Cited
1980
Highly Cited
1980
Methotrexate-induced misincorporation of uracil into DNA.
A line of human lymphoid cells was tested for the presence of dUMP in DNA with or without treatment with the dihydrofolate… 
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