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5,8,11-eicosatriynoic acid

National Institutes of Health

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Fatty Acids, Unsaturated

Papers overview

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2006
2006
Platelet-induced growth of human fibroblasts is associated with an increased expression of 5-lipoxygenase
Summary Proliferation of fibroblasts is vital for adequate wound healing but is probably also involved in different… 
2000
2000
Eicosatetraynoic and eicosatriynoic acids, lipoxygenase inhibitors, block meiosis via antioxidant action.
We previously showed that nordihydroguaiaretic acid (NDGA) and other antioxidants inhibit the resumption of meiosis in oocyte… 
1996
1996
Co-oxidation of all-trans retinol acetate by human term placental lipoxygenase and soybean lipoxygenase.
1993
1993
Purification and partial characterization of lipoxygenase with dual catalytic activities from human term placenta.
Lipoxygenase possessing dual catalytic activities, i.e. dioxygenase and hydroperoxidase, was purified from the cytosols of term… 
1992
1992
Some aspects of activation and inhibition of rat brain lipoxygenase.
Highly Cited
1991
Highly Cited
1991
Glucose induces lipid peroxidation and inactivation of membrane‐associated ion‐transport enzymes in human erythrocytes in vivo and in vitro
Erythrocytes of diabetic subjects (non‐insulin dependent) were found to have eight‐ to ten‐fold higher levels of endogenously… 
1987
1987
Synergistic enhancement of mitogen responses of human lymphocytes by inhibitors of cyclo-oxygenase and 5,8,11-eicosatriynoic acid, an inhibitor of 12-lipoxygenase and leukotriene biosynthesis.
Blood mononuclear cells are well-known producers of various cyclo-oxygenase and lipoxygenase metabolites of arachidonic acid… 
1985
1985
Metabolism of [1-14C]-arachidonic acid by cultured calf aortic endothelial cells: evidence for the presence of a lipoxygenase pathway.
Highly Cited
1980
Highly Cited
1980
Inhibition of leukotriene C and leukotriene D biosynthesis.
1980
1980
Indomethacin inhibits bone resorption and lysosomal enzyme release from bone in organ culture.
The effect of indomethacin on bone resorption was studied in an organ culture system, using calvarial bones from 6--7-day-old… 
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