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4-iodopyrazole

Known as: 4-iodo-1H-pyrazole 
National Institutes of Health

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Pyrazoles

Papers overview

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2016
2016
Rapid experimental SAD phasing and hot-spot identification with halogenated fragments
4-Bromopyrazole and 4-iodopyrazole bind to many small molecule binding hot spots in target proteins. This promiscuous binding… 
2015
2015
Experimental and DFT Study on the Compounds [PdCl2L2] (L = 4-methylpyrazole, 4-iodopyrazole).
Theoretical molecular structures of the complexes [PdCl(2)(HmPz)(2)] (1) and [PdCl(2)(HIPz)(2)] (2) (HmPz = 4-methylpyrazole… 
2014
2014
Synthesis and characterisation of the complete series of B-N analogues of triptycene.
The reaction between the bisborate Li2[o-C6H4(BH3)2] and 2 equivalents of an appropriate pyrazole derivative (Hpz(R)) in the… 
2004
2004
Differential effects of 4-iodopyrazole and 3-methylpyrazole on the metabolic activation of methylazoxymethanol to a DNA methylating species by rat liver and rat colon mucosa in vivo
SummaryUsing a hybrid ion-exchange reverse phase HPLC system, we found that F344 rat liver microsomes, in the presence of an… 
1997
1997
Structural Diversity in the Reaction of Mono- and Disubstituted Pyrazoles with Titanium Tetrachloride. Importance of Hydrogen Bonding and Trends in cis/trans Geometry of Binary Adducts with…
Treatment of titanium tetrachloride with 3,5-di-tert-butylpyrazole affords the complexes [3,5-(C(CH(3))(3))(2)C(3)H(3)N(2)](2… 
1988
1988
Induction of rat hepatic microsomal drug metabolizing enzymes by pyrazole and 4-substituted pyrazoles.
Pyrazole and 4-methylpyrazole are potent inhibitors of liver alcohol dehydrogenase and as such have been proposed as potential… 
1987
1987
The capacity of macrophages from different murine tissues to metabolise ethanol and generate an ethanol-dependent non-dialysable cytotoxic activity in vitro.
Tissue macrophages obtained from liver, bone marrow, spleen and thymus of C57 BL/6 mice closely resembled blood-monocyte-derived… 
1975
1975
Blockade of hepatic aldehyde dehydrogenase in mice on chronic ingestion of 4-bromopyrazole and 4-iodopyrazole.
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