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4-iodopyrazole

Known as: 4-iodo-1H-pyrazole 
National Institutes of Health

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Pyrazoles

Papers overview

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2004
2004
Axial ligand complexes of the Rhodnius nitrophorins: reduction potentials, binding constants, EPR spectra, and structures of the 4-iodopyrazole and imidazole complexes of NP4
Previously, we utilized 4-iodopyrazole (4IPzH) as a heavy atom derivative for the initial solution of the crystal structure of… 
2004
2004
Differential effects of 4-iodopyrazole and 3-methylpyrazole on the metabolic activation of methylazoxymethanol to a DNA methylating species by rat liver and rat colon mucosa in vivo
SummaryUsing a hybrid ion-exchange reverse phase HPLC system, we found that F344 rat liver microsomes, in the presence of an… 
1997
1997
Structural Diversity in the Reaction of Mono- and Disubstituted Pyrazoles with Titanium Tetrachloride. Importance of Hydrogen Bonding and Trends in cis/trans Geometry of Binary Adducts with…
Treatment of titanium tetrachloride with 3,5-di-tert-butylpyrazole affords the complexes [3,5-(C(CH(3))(3))(2)C(3)H(3)N(2)](2… 
1996
1996
X-ray structure of human beta3beta3 alcohol dehydrogenase. The contribution of ionic interactions to coenzyme binding.
The three-dimensional structure of the human beta3beta3 dimeric alcohol dehydrogenase (beta3) was determined to 2.4-A resolution… 
Highly Cited
1994
Highly Cited
1994
Structures of three human beta alcohol dehydrogenase variants. Correlations with their functional differences.
The three-dimensional structures of three variants of human beta alcohol dehydrogenase have been determined to 2.5 A resolution… 
1991
1991
Inducibility of P450Coh by pyrazole and its derivatives.
1989
1989
Role of superoxide anion radicals in ethanol metabolism by blood monocyte-derived human macrophages
The effects of a number of additives on the rate of conversion of ethanol (1 mg/ml; 21.7 mM) to acetate by monolayers of blood… 
1987
1987
The capacity of macrophages from different murine tissues to metabolise ethanol and generate an ethanol-dependent non-dialysable cytotoxic activity in vitro.
Tissue macrophages obtained from liver, bone marrow, spleen and thymus of C57 BL/6 mice closely resembled blood-monocyte-derived… 
1986
1986
Observations on the biochemical basis of ethanol metabolism by human macrophages.
The metabolism of ethanol (0.1 and 1.0 mg/ml) to acetate by blood-monocyte-derived macrophages was only slightly inhibited by… 
Highly Cited
1982
Highly Cited
1982
Pyrazole binding in crystalline binary and ternary complexes with liver alcohol dehydrogenase.
Pyrazole is a strong inhibitor of liver alcohol dehydrogenase in combination with oxidized coenzyme NAD+. We have studied three… 
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