4-aminopiperidine

 
National Institutes of Health

Topic mentions per year

Topic mentions per year

1947-2018
012319472017

Papers overview

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2012
2012
A new series of potent TG2 inhibitors are reported that employ a 4-aminopiperidine core bearing an acrylamide warhead. We… (More)
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2011
2011
4-Aminopiperidines are a variety of therapeutic agents that are extensively metabolized by cytochrome P450s with CYP3A4 as a… (More)
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2009
2009
A series of 44 4-aminopiperidine derivatives was screened in vitro against four protozoan parasites (Trypanosoma brucei… (More)
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2008
2008
Fragment-based screening identified 7-azaindole as a protein kinase B inhibitor scaffold. Fragment elaboration using iterative… (More)
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2005
2005
A series of compounds with potent activity against a multi-drug-resistant strain of Plasmodium falciparum, the causative agent of… (More)
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2004
2004
Several compounds with a 4-aminopiperidine scaffold decorated on both nitrogen atoms by alkyl or acyl moieties containing the… (More)
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2003
2003
We have synthesized a series of C7-piperidine- and 4-aminopiperidine-substituted naphthyridinones, quinolinones, and… (More)
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2003
2003
Extrusion of one of the nitrogens of the piperazine ring of potent nootropic drugs previously described gave 4-aminopiperidine… (More)
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2001
2001
The preparation and structure-activity relationships (SARs) of potent agonists of the human beta(3)-adrenergic receptor (AR… (More)
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1997
1997
We have discovered two substituted 4-aminopiperidine compounds having high in vitro affinity and selectivity for the human… (More)
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