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4-aminopiperidine

National Institutes of Health

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Piperidines

Papers overview

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2020
2020
Preparation of a First 18F-Labeled Agonist for M1 Muscarinic Acetylcholine Receptors
M1 muscarinic acetylcholine receptors (mAChRs) are abundant in postsynaptic nerve terminals of all forebrain regions and have… 
2013
2013
Synthesis and Anti‐Plasmodium Activity of Benzimidazole Analogues Structurally Related to Astemizole
A series of compounds structurally related to astemizole were designed and synthesized with the goal of determining their anti… 
2010
2010
Evaluation of a 4-aminopiperidine replacement in several series of CCR5 antagonists.
2009
2009
Antiprotozoal Activity of 1-Phenethyl-4-Aminopiperidine Derivatives
ABSTRACT A series of 44 4-aminopiperidine derivatives was screened in vitro against four protozoan parasites (Trypanosoma brucei… 
2007
2007
Palladium-mediated N-arylation of heterocyclic diamines: insights into the origin of an unusual chemoselectivity.
The chemoselectivity of the palladium-mediated reaction of bromobenzene with various heterocyclic diamines was studied. Whatever… 
2002
2002
New pyridobenzodiazepine derivatives: modifications of the basic side chain differentially modulate binding to dopamine (D(4.2), D(2L)) and serotonin (5-HT(2A)) receptors.
A series of new pyridobenzodiazepines with variation of the basic side chain were synthesized and evaluated for their binding to… 
2001
2001
4-Aminopiperidine ureas as potent selective agonists of the human beta(3)-adrenergic receptor.
1998
1998
Homo-Freidinger Lactams: Stereoselective Synthesis of 4-Aminopiperidin-2-one Derivatives from Aspartic Acid
β 2b α 4b c 
1997
1997
Substituted 4-aminopiperidines having high in vitro affinity and selectivity for the cloned human dopamine D4 receptor.
1991
1991
Quinolone antibacterials: preparation and activity of bridged bicyclic analogues of the C7-piperazine.
A series of quinolone and naphthyridine antibacterial agents possessing as the C7-heterocycle bicyclic 2,5-diazabicyclo[n.2.m… 
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