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3p14.2

A chromosome band present on 3p
National Institutes of Health

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3 relations
Chromosome 3 Short ArmChromosomesFHIT wt Allele

Papers overview

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Highly Cited
2003
Highly Cited
2003
WW domain containing oxidoreductase gene expression is altered in non-small cell lung cancer.
WWOX (WW domain containing oxidoreductase), a putative tumor suppressor gene that maps to the common fragile site FRA16D on… 
2003
2003
Low expression of fragile histidine triad gene correlates with high proliferation in head and neck squamous cell carcinoma.
Highly Cited
2002
Highly Cited
2002
Identification of unstable sequences within the common fragile site at 3p14.2: implications for the mechanism of deletions within fragile histidine triad gene/common fragile site at 3p14.2 in tumors.
The FRA3B, at 3p14.2, lies within the fragile histidine triad (FHIT) gene and is the most highly expressed of the common fragile… 
Highly Cited
2001
Highly Cited
2001
Loss of Fhit expression is a predictor of poor outcome in tongue cancer.
Abnormalities of FHIT, a candidate tumor suppressor gene located at 3pl4.2, have been found frequently in multiple tumor types… 
Highly Cited
1999
Highly Cited
1999
Reduced Fhit expression in sporadic and BRCA2-linked breast carcinomas.
Evidence for alteration of the FHIT gene in a significant fraction of breast carcinomas has been reported, in apparent… 
Highly Cited
1996
Highly Cited
1996
Molecular analysis of the FHIT gene at 3p14.2 in lung cancer cell lines.
Chromosome 3p is frequently deleted in various cancers including examples in the lung. A novel gene, termed FHIT, was recently… 
Highly Cited
1996
Highly Cited
1996
Direct cloning of DNA sequences from the common fragile site region at chromosome band 3p14.2.
Despite several lines of evidence suggesting that common chromosomal fragile sites are biologically important as hot spots for… 
Highly Cited
1996
Highly Cited
1996
A 350-kb cosmid contig in 3p14.2 that crosses the t(3;8) hereditary renal cell carcinoma translocation breakpoint and 17 aphidicolin-induced FRA3B breakpoints.
The constitutive fragile site at human chromosomal band 3p14.2, FRA3B, has been described as the most active common fragile site… 
1988
1988
Do human renal cell carcinomas arise by a double-loss mechanism?
Highly Cited
1987
Highly Cited
1987
Increased fragile sites and sister chromatid exchanges in bone marrow and peripheral blood of young cigarette smokers.
Cigarette smoking is considered to be the single most important acquired cause of cancer mortality. Studies of chromosome… 
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