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3-tropinone

Known as: 8-methyl-8-azabicyclo(3.2.1)octan-3-one, tropinone 
National Institutes of Health

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Broader (1)

Tropanes

Papers overview

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2012
2012
Lessons from natural products chemistry can offer novel approaches for synthetic chemistry in drug discovery.
After several decades of decline in NPs research we haverecently seen a real explosion of interest in natural-basedcompounds… 
2010
2010
N-Methyl stereochemistry in tropinone: the conformational flexibility of the tropane motif.
The intrinsic conformational and structural properties of the tropinone azabicycle have been investigated in a supersonic jet… 
Highly Cited
2005
Highly Cited
2005
Molecular dissection of tropisetron, an α7 nicotinic acetylcholine receptor-selective partial agonist
Highly Cited
2002
Highly Cited
2002
Enantioselective epoxidation of alkenes catalyzed by 2-fluoro-N-carbethoxytropinone and related tropinone derivatives.
Several alpha-substituted N-carbethoxytropinones have been evaluated as catalysts for asymmetric epoxidation of alkenes with… 
2000
2000
Influence of feeding precursors on tropane alkaloid production during an abiotic stress in Datura innoxia transformed roots
The effects of feeding tropane alkaloid precursors in transformed root culture of Datura innoxia Mill. were studied during a… 
1999
1999
Structures and expression patterns of two tropinone reductase genes from Hyoscyamus niger.
In the biosynthesis of tropane alkaloids, two tropinone reductases (TRs) catalyze reduction of tropinone to different… 
1999
1999
Syntheses of New Open-Ring and homo-Epibatidine Analogues from Tropinone.
1994
1994
Calystegines as a new group of tropane alkaloids in Solanaceae
Calystegines are a new group of polyhydroxy alkaloids with a nortropane skeleton. They were detected in Atropa belladonna root… 
1994
1994
Opposite stereospecificity of two tropinone reductases is conferred by the substrate-binding sites.
Two tropinone reductases (TRs) catalyze opposite stereospecific reductions at a branching point in the biosynthetic pathway of… 
1992
1992
Levels of tropinone-reductase activities influence the spectrum of tropane esters found in transformed root cultures of Datura stramonium L.
The nortropane sulphur analogues 8-thiabicyclo[3.2.1] octan-3-one, 8-thiabicyclo[3.2.1]octan-3a-ol and 8-thiabicyclo[3.2.1]octan… 
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