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3-methyladenine

Known as: 3-MA nucleobase, N(3)-methyladenine 
 
National Institutes of Health

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Highly Cited
2015
Highly Cited
2015
ABSTRACT Zika virus (ZIKV) is an emerging arbovirus of the Flaviviridae family, which includes dengue, West Nile, yellow fever… Expand
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Highly Cited
2010
Highly Cited
2010
A group of phosphoinositide 3-kinase (PI3K) inhibitors, such as 3-methyladenine (3-MA) and wortmannin, have been widely used as… Expand
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Highly Cited
2008
Highly Cited
2008
Hypoxia (lack of oxygen) is a physiological stress often associated with solid tumors. Hypoxia correlates with poor prognosis… Expand
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Highly Cited
2007
Highly Cited
2007
Autophagy is an intracellular bulk degradation process for proteins and organelles. In the heart, autophagy is stimulated by… Expand
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Highly Cited
2005
Highly Cited
2005
ABSTRACT Mammalian cells were observed to die under conditions in which nutrients were depleted and, simultaneously… Expand
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Highly Cited
2004
Highly Cited
2004
AbstractAutophagy is originally named as a process of protein recycling. It begins with sequestering cytoplasmic organelles in a… Expand
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Highly Cited
2001
Highly Cited
2001
The mechanisms underlying neoplastic epithelial cell killing by ionizing radiation are largely unknown. We discovered a novel… Expand
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Highly Cited
2000
Highly Cited
2000
3-Methyladenine which stops macroautophagy at the sequestration step in mammalian cells also inhibits the phosphoinositide 3… Expand
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Highly Cited
1997
Highly Cited
1997
Recent studies indicate that phosphatidylinositol 3-kinase is essential in the regulation of many processes dependent on membrane… Expand
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Highly Cited
1982
Highly Cited
1982
3-Methyladenine (5 mM) inhibits endogenous protein degradation in isolated rat hepatocytes by about 60%, while having no adverse… Expand
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