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3-methyladenine

Known as: 3-MA nucleobase, N(3)-methyladenine 
National Institutes of Health

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2 relations

Broader (1)

Adenine
analogs & derivatives

Papers overview

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Highly Cited
2010
Highly Cited
2010
Autophagic cell death induced by 5-FU in Bax or PUMA deficient human colon cancer cell.
Highly Cited
2004
Highly Cited
2004
Genotoxicity of acrylamide in human lymphocytes.
Highly Cited
1998
Highly Cited
1998
Mammalian 3-methyladenine DNA glycosylase protects against the toxicity and clastogenicity of certain chemotherapeutic DNA cross-linking agents.
DNA repair status is recognized as an important determinant of the clinical efficacy of cancer chemotherapy. To assess the role… 
Highly Cited
1996
Highly Cited
1996
Excision of DNA adducts of nitrogen mustards by bacterial and mammalian 3-methyladenine-DNA glycosylases.
Nitrogen mustards are among the DNA alkylating agents most widely used in chemotherapy. The homogeneous Escherichia coli AlkA… 
Highly Cited
1994
Highly Cited
1994
1,N6-ethenoadenine is preferred over 3-methyladenine as substrate by a cloned human N-methylpurine-DNA glycosylase (3-methyladenine-DNA glycosylase).
A lethal DNA adduct induced by methylating agents, 3-methyladenine (m3A), is removed by both the constitutive (Tag) and inducible… 
Highly Cited
1989
Highly Cited
1989
Monofunctional alkylating agent-induced S-phase-dependent DNA damage.
Highly Cited
1986
Highly Cited
1986
Regulatory mechanisms for induction of synthesis of repair enzymes in response to alkylating agents: ada protein acts as a transcriptional regulator.
Expression of the ada and alkA genes, both of which are involved in the adaptive response of Escherichia coli to alkylating… 
Highly Cited
1973
Highly Cited
1973
The pattern of methylated purines formed in DNA of intact and regenerating liver of rats treated with the carcinogen dimethylnitrosamine.
Highly Cited
1973
Highly Cited
1973
Biological implications of the instability of the N-glycosidic bone of 3-methyldeoxyadenosine in DNA.
Highly Cited
1964
Highly Cited
1964
METHYLATION OF DEOXYRIBONUCLEIC ACID BY DIAZOMETHANE.
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