3-ketoaphidicolin
National Institutes of Health
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We used gas chromatography/mass spectrometry to identify and quantitate some aphidicolin metabolites in plasma and urine of…
1. Aphidicolin is shown to undergo rapid metabolism by rat-liver microsomes resulting in its inactivation and loss of its DNA…
Microbial transformation experiments were conducted using 3-ketoaphidicolin (2) as a starting material. Metabolites were isolated…