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3-hydroxymexiletine

Known as: 1-(2,6-dimethyl-3-hydroxyphenoxy)-2-aminopropane, m-hydroxymexiletine, meta-hydroxymexiletine 
National Institutes of Health

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Broader (1)

Mexiletine
analogs & derivatives

Papers overview

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1999
1999
Stereoselective disposition of the antiarrhythmic agent mexiletine during the concomitant administration of caffeine.
Caffeine consumption is extensive in industrialized countries and its role in drug-drug interactions is often overlooked. CYP1A2… 
1997
1997
Stereoselective metabolism of rac-mexiletine by the fungus Cunninghamella echinulata yields the major human metabolites hydroxymethylmexiletine and p-hydroxymexiletine.
rac-Mexiletine is an orally effective class 1b antiarrhythmic agent used to treat ventricular arrhythmias. In vivo experiments… 
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