3-decynoyl-N-acetylcysteamine

In vitro experiments with modular polyketide synthases (PKSs) are often limited by the availability of polyketide extender units… Expand

Expression of six genes from two glutamate fermenting clostridia converted Escherichia coli into a producer of glutaconate from 2… Expand

LovF is a highly reducing polyketide synthase (HR-PKS) from the filamentous fungus Aspergillus terreus. LovF synthesizes the… Expand

Curcuminoids found in the rhizome of turmeric, Curcuma longa, possess various biological activities. Despite much attention… Expand

Nonribosomal peptide synthetases (NRPSs) carry out the biosynthesis of numerous peptide natural products, including many with… Expand

6-Deoxyerythronolide B synthase (DEBS) is the modular polyketide synthase (PKS) that catalyzes the biosynthesis of 6… Expand

BACKGROUND Aflatoxin B1 (compound 5. ) is a potent environmental carcinogen produced by certain Aspergillus species. Its first… Expand

A Diels-Alder cyclization proposed to occur during polyketide synthase assembly of the bicyclic core of lovastatin (1) (mevinolin… Expand

Abstract Soybean lipoxidase and prostaglandin synthetase from sheep seminal vesicles are subject to powerful inhibition by 5,8,11… Expand

Abstract β-Hydroxydecanoyl-thioester dehydrase is known to be the enzyme responsible for the introduction of the double bond into… Expand