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3-decynoyl-N-acetylcysteamine

 
National Institutes of Health

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2 relations

Broader (1)

Cysteamine
analogs & derivatives

Papers overview

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2011
2011
Enzymatic extender unit generation for in vitro polyketide synthase reactions: structural and functional showcasing of Streptomyces coelicolor MatB.
In vitro experiments with modular polyketide synthases (PKSs) are often limited by the availability of polyketide extender units… Expand
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2011
2011
Substrate specificity of 2-hydroxyglutaryl-CoA dehydratase from Clostridium symbiosum: toward a bio-based production of adipic acid.
Expression of six genes from two glutamate fermenting clostridia converted Escherichia coli into a producer of glutaconate from 2… Expand
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2009
2009
Curcuminoid biosynthesis by two type III polyketide synthases in the herb Curcuma longa.
Curcuminoids found in the rhizome of turmeric, Curcuma longa, possess various biological activities. Despite much attention… Expand
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2009
2009
Acyltransferase mediated polyketide release from a fungal megasynthase.
LovF is a highly reducing polyketide synthase (HR-PKS) from the filamentous fungus Aspergillus terreus. LovF synthesizes the… Expand
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2004
2004
Type II thioesterase restores activity of a NRPS module stalled with an aminoacyl-S-enzyme that cannot be elongated.
Nonribosomal peptide synthetases (NRPSs) carry out the biosynthesis of numerous peptide natural products, including many with… Expand
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2004
2004
Probing biosynthesis of plant polyketides with synthetic N-acetylcysteamine thioesters.
Recombinant chalcone synthase (CHS) from Scutellaria baicalensis accepted cinnamoyl diketide-NAC and cinnamoyl-NAC as a substrate… Expand
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2004
2004
Chemo- and regioselective peptide cyclization triggered by the N-terminal fatty acid chain length: the recombinant cyclase of the calcium-dependent antibiotic from Streptomyces coelicolor.
Here we report the first biochemical characterization of a recombinant nonribosomal peptide cyclase of a streptomycete, the model… Expand
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2001
2001
Assessing the balance between protein-protein interactions and enzyme-substrate interactions in the channeling of intermediates between polyketide synthase modules.
6-Deoxyerythronolide B synthase (DEBS) is the modular polyketide synthase (PKS) that catalyzes the biosynthesis of 6… Expand
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1996
1996
Demonstration of the catalytic roles and evidence for the physical association of type I fatty acid synthases and a polyketide synthase in the biosynthesis of aflatoxin B1.
BACKGROUND Aflatoxin B1 (compound 5. ) is a potent environmental carcinogen produced by certain Aspergillus species. Its first… Expand
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1968
1968
The antibacterial activity of 3-decynoyl-n-acetylcysteamine. Inhibition in vivo of beta-hydroxydecanoyl thioester dehydrase.
  • Leon R. Kass
  • The Journal of biological chemistry
  • 1968
    • Corpus ID: 5904234
Abstract β-Hydroxydecanoyl-thioester dehydrase is known to be the enzyme responsible for the introduction of the double bond into… Expand
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