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3'-hydroxyamobarbital

Known as: 5-ethyl-5-(3-hydroxy-3-methylbutyl)-2,4,6(1H,3H,5H)-pyrimidinetrione 
 
National Institutes of Health

Papers overview

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1983
1983
Amobarbital metabolism in human liver and in rat liver, lung, kidney, and small intestine was measured in vitro using thin-layer… Expand
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1980
1980
Amobarbital is almost completely metabolized in animals and man. The major metabolite is 3'-hydroxyamobarbital. The second major… Expand
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Review
1979
Review
1979
The two main metabolites of amobarbital excreted in urine are 3'-hydroxyamobarbital (C-OH) and 1-(beta-D-glucopyranosyl… Expand
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1978
1978
This paper establishes that the relative proportion of amobarbital metabolites in urine is highly variable from person to person… Expand
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1977
1977
An accurate and sensitive g.c.m.s. procedure was developed to determine both N-hydroxyamobarbital and 3′-hydroxyamobarbital… Expand
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1977
1977
It has been shown recently that the overall metabolism of amobarbital in man is essentially under genetic control. The drug… Expand
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1975
1975
After oral administration of 14C-labeled amobarbital to healthy subjects, most of the radioactivity was recovered in urine and… Expand
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1974
1974
1. Comparative studies on the distribution and metabolism of [2-14C]amobarbital following 50 mg/kg intraperitoneal doses in non… Expand
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