Skip to search formSkip to main contentSkip to account menu

3,4-dihydroxyphenylacetaldehyde

Known as: DHPAA aldehyde 
National Institutes of Health

Related topics

Related topics

2 relations

Broader (1)

3,4-Dihydroxyphenylacetic Acid
analogs & derivatives

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2019
2019
3,4-Dihydroxyphenylacetaldehyde Is More Efficient than Dopamine in Oligomerizing and Quinonizing α-Synuclein
Lewy body diseases such as Parkinson’s disease involve intraneuronal deposition of the protein α-synuclein (AS) and depletion of… 
Highly Cited
2014
Highly Cited
2014
Neuroprotective effects of aldehyde dehydrogenase 2 activation in rotenone-induced cellular and animal models of parkinsonism
Review
2013
Review
2013
Biomarkers, mechanisms, and potential prevention of catecholamine neuron loss in Parkinson disease.
Highly Cited
2012
Highly Cited
2012
Vesicular uptake blockade generates the toxic dopamine metabolite 3,4‐dihydroxyphenylacetaldehyde in PC12 cells: relevance to the pathogenesis of Parkinson's disease
Parkinson's disease entails profound loss of nigrostriatal dopaminergic terminals, decreased vesicular uptake of intraneuronal… 
2011
2011
Dopamine-derived biological reactive intermediates and protein modifications: Implications for Parkinson's disease.
Highly Cited
2000
Highly Cited
2000
Metabolic stress in PC12 cells induces the formation of the endogenous dopaminergic neurotoxin, 3,4‐dihydroxyphenylacetaldehyde
3,4‐Dihydroxyphenylacetaldehyde (DOPAL) has been reported to be a toxic metabolite formed by the oxidative‐deamination of… 
Highly Cited
1991
Highly Cited
1991
Human aldehyde dehydrogenase. Activity with aldehyde metabolites of monoamines, diamines, and polyamines.
Highly Cited
1988
Highly Cited
1988
Human brain "high Km" aldehyde dehydrogenase: purification, characterization, and identification as NAD+ -dependent succinic semialdehyde dehydrogenase.
Highly Cited
1986
Highly Cited
1986
Stereospecific deuterium substitution at the alpha-carbon position of dopamine and its effect on oxidative deamination catalyzed by MAO-A and MAO-B from different tissues.
Highly Cited
1977
Highly Cited
1977
Decarboxylation-dependent transamination catalyzed by mammalian 3,4-dihydroxyphenylalanine decarboxylase.
By clicking accept or continuing to use the site, you agree to the terms outlined in our Privacy Policy (opens in a new tab), Terms of Service (opens in a new tab), and Dataset License (opens in a new tab)