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2MeSADP

National Institutes of Health

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methylthio-ADP

Papers overview

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2016
2016
Nucleotides protect rat brain astrocytes against hydrogen peroxide toxicity and induce antioxidant defense via P2Y receptors
2016
2016
Purinergic P2Y1 Receptors Control Rapid Expression of Plasma Membrane Processes in Hippocampal Astrocytes
Astrocytes regulate neuronal activity and blood brain barrier through tiny plasma membrane branches or astrocytic processes (APs… 
2015
2015
Cross talk between serine/threonine and tyrosine kinases regulates ADP-induced thromboxane generation in platelets
Summary ADP-induced thromboxane generation depends on Src family kinases (SFKs) and is enhanced with pan-protein kinase C (PKC… 
2010
2010
Mechanism underlying endothelium-dependent relaxation by 2-methylthio-ADP in monkey cerebral artery.
We recently reported endothelium-dependent relaxation caused by nucleotides in the non-human primate cerebral artery. Here, we… 
2010
2010
ACETYLSALICYLIC ACID ENHANCES PURINERGIC RECEPTOR‐MEDIATED OUTWARD CURRENTS IN RAT MEGAKARYOCYTES
Megakaryocytes (MKs) as platelet progenitor cells are a relevant model for platelet reactivity. Patch clamp techniques were used… 
2010
2010
Purinergic receptor-mediated morphological changes in microglia are transient and independent from inflammatory cytokine release.
2008
2008
Functional characterization of P2Y1 versus P2X receptors in RBA‐2 astrocytes: Elucidate the roles of ATP release and protein kinase C
A physiological concentration of extracellular ATP stimulated biphasic Ca2+ signal, and the Ca2+ transient was decreased and the… 
Highly Cited
2004
Highly Cited
2004
Adenine triphosphate nucleotides are antagonists at the P2Y12 receptor
Summary.   The aim of the present study was to characterize the pharmacological profile of the P2Y12 receptor for several adenine… 
2002
2002
2-Chloro N(6)-methyl-(N)-methanocarba-2'-deoxyadenosine-3',5'-bisphosphate is a selective high affinity P2Y(1) receptor antagonist.
1. We reported previously that bisphosphate derivatives of adenosine are antagonists of the P2Y(1) receptor and that modification… 
1992
1992
ADP receptor-induced activation of guanine-nucleotide-binding proteins in human platelet membranes.
ADP receptor-regulated binding of the labeled GTP analog, guanosine 5'-O-(3-[35S]thiotriphosphate) ([35S]GTP[gamma S]), to… 
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