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25-hydroxy vitamin D3 1-alpha-hydroxylase activity

Known as: 25-OHD-1 alpha-hydroxylase activity, 25-hydroxycholecalciferol 1-monooxygenase activity, calcidiol 1-monooxygenase activity 
Catalysis of the reaction: calcidiol + H(+) + NADPH + O(2) = calcitriol + H(2)O + NADP(+). [EC:1.14.13.13, RHEA:20576]
National Institutes of Health

Related topics

Related topics

3 relations
CYP27B1 protein, humanCalcidiol 1-Monooxygenase

Broader (1)

calcitriol biosynthetic process from calciol

Papers overview

Semantic Scholar uses AI to extract papers important to this topic.
2010
2010
Pseudo vitamin D deficiency rickets in pigs: in vitro measurements of renal 25-hydroxycholecalciferol-1-hydroxylase activity.
Summary The activity of renal 25-hydroxycholecalciferol-1-hydroxylase was studied in in vitro preparations of normal healthy… 
1993
1993
Survival of vitamin D-deficient embryos: time and choice of cholecalciferol or its metabolites for treatment in ovo.
Vitamin D-deficient (-D) Japanese quail embryos [from hens fed 1,25-dihydroxycholecalciferol (1,25-(OH)2D3)] die at Day 15 of… 
1986
1986
Absence of renal 25-hydroxycholecalciferol-1-hydroxylase activity in a pig strain with vitamin D-dependent rickets
SummaryCholecalciferol-1-hydroxylase activities were estimated in renal cortex homogenates and mitochondrial preparations from… 
1984
1984
The lack of relationships between vitamin D3 metabolites and calcium-binding protein in the eggshell gland of laying birds.
1983
1983
The effect of betamethasone on duodenal calcium absorption and 1,25-dihydroxy vitamin D3 production in the chick.
Duodenal absorption of calcium, renal 25-hydroxycholecalciferol-1-hydroxylase activity, percentage bone ash, growth rate and… 
1980
1980
The 25‐hydroxycholecalciferol‐1‐hydoxylase activity of chick kidney cells: direct effect of parathyroid
Highly Cited
1979
Highly Cited
1979
The interaction between dietary calcium and gonadal hormones in their effect on plasma calcium, bone, 25-hydroxycholecalciferol-1-hydroxylase, and duodenal calcium-binding protein, measured by a…
Male chicks, fed low, normal, or high calcium- and cholecalciferol-containing diets for 14 days, were given three combined… 
1978
1978
Calcium-binding protein and kidney 25-hydroxycholecalciferol-1-hydroxylase activity in turkey poults.
A vitamin D-dependent calcium-binding protein (CaBP) has been found in the intestinal mucosa of turkeys (Meleagris gallopavo… 
Highly Cited
1975
Highly Cited
1975
Presence of renal 25-hydroxyvitamin-D-1-hydroxylase in species of all vertebrate classes.
  • H. HenryA. Norman
  • Comparative biochemistry and physiology. B…
  • 1975
  • Corpus ID: 11037687
1973
1973
Direct control by calcium of 25-hydroxycholecalciferol-1-hydroxylase activity in chick kidney mitochondria.
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