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2-oxothiazolidine-4-carboxylate

Known as: L-2-oxothiazolidine-4-carboxylate 
National Institutes of Health

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Broader (1)

2-oxothiazolidine-4-carboxylic acid

Papers overview

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Highly Cited
2012
Highly Cited
2012
The influence of glutathione on redox regulation by antioxidant proteins and apoptosis in macrophages exposed to 2-hydroxyethyl methacrylate (HEMA).
2009
2009
L-2-Oxothiazolidine-4-carboxylate reverses glutathione oxidation and delays fatigue of skeletal muscle in vitro.
Fatiguing exercise promotes oxidation of intracellular thiols, notably glutathione. Interventions that oppose or reverse thiol… 
Highly Cited
2005
Highly Cited
2005
The use of zebrafish for assessing ototoxic and otoprotective agents
Review
2004
Review
2004
Glutathione metabolism and its implications for health.
Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione… 
Highly Cited
2004
Highly Cited
2004
Preventive effect of antioxidants in MPTP-induced mouse model of Parkinson's disease
Highly Cited
1998
Highly Cited
1998
Role of glutathione in protection against noise-induced hearing loss
Highly Cited
1997
Highly Cited
1997
A trial of antioxidants N-acetylcysteine and procysteine in ARDS. The Antioxidant in ARDS Study Group.
OBJECTIVE To determine the levels of glutathione and cysteine in patients with ARDS and examine the effect of treatment with N… 
Highly Cited
1990
Highly Cited
1990
L-2-oxothiazolidine-4-carboxylate as a cysteine precursor: efficacy for growth and hepatic glutathione synthesis in chicks and rats.
Chick and rat experiments were conducted to determine the efficacy of L-2-oxothiazolidine-4-carboxylate (OTC) as a cysteine (Cys… 
Highly Cited
1985
Highly Cited
1985
Enhancement of intracellular glutathione protects endothelial cells against oxidant damage.
Highly Cited
1981
Highly Cited
1981
Stimulation of hepatic glutathione formation by administration of L-2-oxothiazolidine-4-carboxylate, a 5-oxo-L-prolinase substrate.
5-Oxo-L-prolinase, the enzyme that catalyzes the conversion of 5-oxo-L-proline to L-glutamate coupled to the cleavage of ATP to… 
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