2-oxothiazolidine-4-carboxylate

Fatiguing exercise promotes oxidation of intracellular thiols, notably glutathione. Interventions that oppose or reverse thiol… Expand

Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione… Expand

The ability of neurons to metabolize sulfur-containing compounds to cysteine was investigated using as indicator the glutathione… Expand

OBJECTIVE To determine the levels of glutathione and cysteine in patients with ARDS and examine the effect of treatment with N… Expand

The efficiency of L-2-oxothiazolidine-4-carboxylate, a cysteine precursor, in stimulating glutathione synthesis and growth was… Expand

Chick and rat experiments were conducted to determine the efficacy of L-2-oxothiazolidine-4-carboxylate (OTC) as a cysteine (Cys… Expand

Sterile L-2-oxothiazolidine-4-carboxylate, given as a neutral 100 mmol solution at a dose of 8 mmol/kg subcutaneously, caused an… Expand

Although brain cysteine levels can be increased by administration of cysteine, treatment with this amino acid causes toxicity. L… Expand

Depletion of glutathione by inhibition of its synthesis by buthionine sulfoximine, an irreversible inhibitor of gamma… Expand

5-Oxo-L-prolinase, the enzyme that catalyzes the conversion of 5-oxo-L-proline to L-glutamate coupled to the cleavage of ATP to… Expand