2-oxothiazolidine-4-carboxylate

Fatiguing exercise promotes oxidation of intracellular thiols, notably glutathione. Interventions that oppose or reverse thiol… Expand

Glutathione (gamma-glutamyl-cysteinyl-glycine; GSH) is the most abundant low-molecular-weight thiol, and GSH/glutathione… Expand

The ability of neurons to metabolize sulfur-containing compounds to cysteine was investigated using as indicator the glutathione… Expand

Glutathione is a major cellular antioxidant that protects protein thiols and inhibits cellular damage due to oxygen free radicals… Expand

OBJECTIVE To determine the levels of glutathione and cysteine in patients with ARDS and examine the effect of treatment with N… Expand

BACKGROUND & AIMS Disturbances of the thiol metabolism of acinar cells may play a role in the pathophysiology of acute… Expand

Chick and rat experiments were conducted to determine the efficacy of L-2-oxothiazolidine-4-carboxylate (OTC) as a cysteine (Cys… Expand

Sterile L-2-oxothiazolidine-4-carboxylate, given as a neutral 100 mmol solution at a dose of 8 mmol/kg subcutaneously, caused an… Expand

Although brain cysteine levels can be increased by administration of cysteine, treatment with this amino acid causes toxicity. L… Expand

5-Oxo-L-prolinase, the enzyme that catalyzes the conversion of 5-oxo-L-proline to L-glutamate coupled to the cleavage of ATP to… Expand