2-oxothiazolidine-4-carboxylate

The aim of the study was to investigate the ameliorative effects and the mechanism of action of L-2-oxothiazolidine-4-carboxylate… (More)

gamma-glutamyl transpeptidase (gamma-GT) deficiency in GGT(enu1) mice is associated with glutathionemia, glutathionuria, growth… (More)

The ability of neurons to metabolize sulfur-containing compounds to cysteine was investigated using as indicator the glutathione… (More)

Glutathione is a major cellular antioxidant that protects protein thiols and inhibits cellular damage due to oxygen free radicals… (More)

The pharmacokinetics of both 2-oxothiazolidine-4-carboxylate (OTZ), a prodrug of cysteine, and total blood cysteine (cysteine… (More)

OBJECTIVE To determine the levels of glutathione and cysteine in patients with ARDS and examine the effect of treatment with N… (More)

Chick and rat experiments were conducted to determine the efficacy of L-2-oxothiazolidine-4-carboxylate (OTC) as a cysteine (Cys… (More)

Sterile L-2-oxothiazolidine-4-carboxylate, given as a neutral 100 mmol solution at a dose of 8 mmol/kg subcutaneously, caused an… (More)

Although brain cysteine levels can be increased by administration of cysteine, treatment with this amino acid causes toxicity. L… (More)

5-Oxo-L-prolinase, the enzyme that catalyzes the conversion of 5-oxo-L-proline to L-glutamate coupled to the cleavage of ATP to… (More)